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. 2020 Apr 23;14(4):e0008035.
doi: 10.1371/journal.pntd.0008035. eCollection 2020 Apr.

Target product profile for a test for the early assessment of treatment efficacy in Chagas disease patients: An expert consensus

Julio Alonso-Padilla  1 , Marcelo Abril  2 , Belkisyolé Alarcón de Noya  3 , Igor C Almeida  4 , Andrea Angheben  5 , Tania Araujo Jorge  6 , Eric Chatelain  7 , Monica Esteva  8 , Joaquim Gascón  1 , Mario J Grijalva  9   10 , Felipe Guhl  11 , Alejandro Marcel Hasslocher-Moreno  12 , Manuel Carlos López  13 , Alejandro Luquetti  14 , Oscar Noya  3 , María Jesús Pinazo  1 , Janine M Ramsey  15 , Isabela Ribeiro  7 , Andres Mariano Ruiz  8 , Alejandro G Schijman  16 , Sergio Sosa-Estani  17   18 , M Carmen Thomas  13 , Faustino Torrico  19 , Maan Zrein  20 , Albert Picado  21
Affiliations

Target product profile for a test for the early assessment of treatment efficacy in Chagas disease patients: An expert consensus

Julio Alonso-Padilla et al. PLoS Negl Trop Dis. .
No abstract available

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Conflict of interest statement

The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. IA, MCL, MCT, AMR, and MZ are involved in the development of serological assays based on parasite-derived biomarkers for the early assessment of treatment response in Chagas disease. No patents applications or other forms of intellectual properties will be considered in this development work.

References

    1. World Health Organization (WHO) Media Centre; Chagas disease (American trypanosomiasis). Fact sheet updated April 2019. Available at: https://www.who.int/news-room/fact-sheets/detail/Chagas-disease-(america.... [cited 2019 Aug 10].
    1. Pérez-Molina JA, Molina I. Chagas disease. Lancet. 2018; 391(10115):82–94. 10.1016/S0140-6736(17)31612-4 - DOI - PubMed
    1. Ribeiro I, Sevcsik AM, Alves F, Diap G, Don R, Harhay MO, et al. New, improved treatments for Chagas disease: from the R&D pipeline to the patients. PLoS Negl Trop Dis. 2009; 3(7):e484 10.1371/journal.pntd.0000484 - DOI - PMC - PubMed
    1. World Health Organization Expert Committee. Control of Chagas disease. WHO Technical Report Series number 905. 2002; Brazilia, Brazil. - PubMed
    1. Organización Panamericana de la Salud (OPS). Guía para el diagnóstico y el tratamiento de la enfermedad de Chagas. 2018; Washington DC, Estados Unidos de América. [Cite in Spanish].

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