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Comment
. 2020 Aug;81(2):318-356.
doi: 10.1016/j.jinf.2020.04.016. Epub 2020 Apr 20.

Bayesian phylodynamic inference on the temporal evolution and global transmission of SARS-CoV-2

Affiliations
Comment

Bayesian phylodynamic inference on the temporal evolution and global transmission of SARS-CoV-2

Jianguo Li et al. J Infect. 2020 Aug.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Bayesian evolutionary dynamics of SARS-CoV-2. (a) Time-scaled Maximum Clade Credibility (MCC) tree based on MCMC analysis of the 99 SARS-CoV-2 genomes with an Exponential Growth tree prior. The time scale was set to the bottom of Fig. 1 shared by both (a) and (b). The tree branches were colored according to the collection countries with the color panel to the left lower part. Time to the Most Common Recent Ancestor (tMRCA) and the divergence time of clades and sub-clades were labelled on the corresponding nodes with 95% HPD in the following bracket. Clade and sub-clade specific mutations were labelled under the divergent time, with the non-synonymous mutations labelled in red. (b) population dynamics of SARS-CoV-2. The viral population dynamics was represented by the viral relative genetic diversity generated from Bayesian Skyline Plot reconstruction of the MCMC analysis. The Y-axis represents relative genetic diversity, which is equivalent to the product of the effective population size (Ne) and the generation length in days (τ). The color regions show 95% HPD limits, and the black line represent the median estimate of relative genetic diversity.

Comment on

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