Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Apr 19;56(4):188.
doi: 10.3390/medicina56040188.

Necrotizing Sialometaplasia and Bulimia: A Case Report

Francisco Salvado  1   2 , Miguel de Araújo Nobre  1   3 , João Gomes  2   4 , Paulo Maia  2
Affiliations
Case Reports

Necrotizing Sialometaplasia and Bulimia: A Case Report

Francisco Salvado et al. Medicina (Kaunas). .

Abstract

Bulimia is an eating disorder with a great prevalence in young women. Due to its multifactor ethiology, bulimia has systemic consequences. In the literature, necrotising sialometaplasia is seldom associated with bulimia. Its etiopathogenesis is discussed by several authors; nevertheless, the consensus does not consider the relevance of local trauma associated with induced vomiting. A case of necrotising sialomethaplasia, presented with a single hard palatal ulcer in a bulimic woman is described in the present report. The patient did not present significant systemic laboratorial values, nor physical weight variations, which highlights the relevance of performing a complete medical clinical history when diagnosing this rare pathology.

Keywords: bulimia; bulimia nervosa; diagnosis; epidemiology; necrotizing sialometaplasia.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Intra-oral photograph of the palatal aspect exhibiting the lesion. Note the edges of the lesion with well-defined limits and the erythematous halo with well-defined limits surrounding the whole lesion.
Figure 2
Figure 2
Intra-oral photograph immediately after performing the incisional biopsy of the lesion.
Figure 3
Figure 3
Photograph immediately after performing the incisional biopsy of the lesion. Note that the biopsy involved both the edges of the lesion, a portion of tissue from the central area of the lesion and healthy tissue of the palate.
Figure 4
Figure 4
Biopsy exhibiting a slightly hyperplastic epithelium, limiting the ulceration surface, with both the foci of necrosis and some minor salivary glands in pre-necrotic status in the underlying connective tissue.
Figure 5
Figure 5
Magnification of the biopsy exhibiting necrosis and inflammatory infiltration of acinar cells, foci of malpighian metaplasia in residual channels and some acini in canalicular transformation.
Figure 6
Figure 6
Intra-oral photograph of the palatal aspect four weeks post-operatively. Note the improvement in the lesion.
Figure 7
Figure 7
Complete healing of the lesion after 8 weeks.
See this image and copyright information in PMC

References

    1. Penner C.R., Thompson L.D. Necrotizing sialometaplasia. Ear Nose Throat J. 2003;82:493–494. doi: 10.1177/014556130308200712. - DOI - PubMed
    1. Gilowski Ł., Wiench R., Polakiewicz-Gilowska A., Dwornicka K. Necrotizing sialometaplasia of the palatal mucosa in patient with history of anorexia: Review and case report. Am. J. Otolaryngol. 2014;35:400–401. doi: 10.1016/j.amjoto.2014.03.001. - DOI - PubMed
    1. Abdalla-Aslan R., Frid H., Totri A., Akrish S., Merhav G., Rachmiel A. Necrotizing sialometaplasia of the palate in a young bodybuilder with anabolic androgenic steroids abuse. Quintessence Int. 2020;20:2–7. doi: 10.3290/j.qi.a44146. - DOI - PubMed
    1. Brannon R.B., Fowler C.B., Hartman K.S. Necrotizing sialometaplasia. A clinicopathologic study of sixty-nine cases and review of the literature. Oral Surg. Oral Med. Oral Pathol. 1991;72:317–325. doi: 10.1016/0030-4220(91)90225-2. - DOI - PubMed
    1. Rye L.A., Calhoun N.R., Redman R.S. Necrotizing sialometaplasia in a patient with Buerger’s disease and Raynaud’s phenomenon. Oral Surg. Oral Med. Oral Pathol. 1980;49:233–236. doi: 10.1016/0030-4220(80)90054-7. - DOI - PubMed

Publication types

LinkOut - more resources