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. 2020 Feb 24;8(4):1914-1922.
doi: 10.1002/fsn3.1477. eCollection 2020 Apr.

Adsorption and controlled release of three kinds of flavors on UiO-66

Deshou Mao  1 , Congjia Xie  2 , Zhiyu Li  1 , Liu Hong  1 , Rongfen Qu  1 , You Gao  2 , Jiao He  2 , Jiaqiang Wang  2
Affiliations

Adsorption and controlled release of three kinds of flavors on UiO-66

Deshou Mao et al. Food Sci Nutr. .

Abstract

Delivery systems for controlled release of fragrances are significantly essential in the flavor and fragrance industry due to a limited life span (premature evaporation and degradation) of fragrance compounds. Recently, several adsorption materials such as porous materials have been developed in delivery systems for targeted fragrance release. In this work, UiO-66, a member of metal-organic framework (MOF) family with high porosity and greater adsorbability, was selected as a prospective alternative to traditional porous adsorbents for controlled release of fragrances. Isophorone, eugenol, and β-ionone with strong aroma are widely used as perfume flavors, soap flavor, cosmetic flavors, and even as a food-flavoring agents, and were chosen as representative fragrances for adsorption and controlled release studies. The adsorption and release behavior of fragrances on UiO-66 was evaluated by high-performance liquid chromatography (HPLC). The UiO-66 with high surface area (1,076 m2/g) achieved effective storage and controlled release for isophorone, eugenol, and β-ionone. The adsorption rates of isophorone, eugenol, and β-ionone can reach 99.4%, 99.9%, and 60.2%, respectively. Additionally, the release of these fragrances from UiO-66 can sustain over 20 days. UiO-66 exhibited higher release rate over eugenol with desorption rates of 95.2% than that of β-ionone (52.6%) and isophorone (49.6%), respectively, suggesting a good adsorption-release selectivity of UiO-66 to different fragrances. This study further confirms the usability of UiO-66 in fragrance release and extends the application of MOF porosity in aroma release.

Keywords: UiO‐66; adsorption and controlled release; eugenol; isophorone; β‐ionone.

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Conflict of interest statement

The authors declare that they do not have any conflict of interest.

Figures

Figure 1
Figure 1
Adsorption curves of UiO‐66 for three fragrances in ethanol solutions and cyclohexane solutions
Figure 2
Figure 2
Effect of adsorbent dose on adsorption of isophorone, eugenol, and β‐ionone in cyclohexane solution
Figure 3
Figure 3
(a) Controlled release curve of isophorone from UiO‐66 at different temperatures. (b) Controlled release curve of eugenol from UiO‐66 at different temperatures. (c) Sustained release curve of β‐ionone from UiO‐66 at different temperatures
Figure 4
Figure 4
Release of fragrances from UiO‐66 at room temperature for 20 days
Figure 5
Figure 5
(a) The corresponding state variation of isophorone loaded UiO‐66 during 20 days of release. (b) The corresponding state variation of eugenol loaded UiO‐66 during 20 days of release. (c) The corresponding state variation of β‐ionone loaded UiO‐66 during 20 days of release
Figure 6
Figure 6
Chemical structures of UiO‐66 in two‐dimensional (2D) view (Zr: blue, O: red, C: gray)
Figure 7
Figure 7
Chemical structures of fragrances in this work (isophorone, eugenol, β‐ionone)
See this image and copyright information in PMC

References

    1. Abid, H. R. , Tian, H. , Ang, H. M. , Tade, M. O. , Buckley, C. E. , & Wang, S. (2012). Nanosize Zr‐metal organic framework (UiO‐66) for hydrogen and carbon dioxide storage. Chemical Engineering Journal, 187, 415–420. 10.1016/j.cej.2012.01.104 - DOI
    1. Bhattacharjee, A. , Gumma, S. , & Purkait, M. K. (2018). Fe3O4 promoted metal organic framework MIL‐100(Fe) for the controlled release of doxorubicin hydrochloride. Microporous and Mesoporous Materials, 259, 203–210. 10.1016/j.micromeso.2017.10.020 - DOI
    1. Cao, Z. H. , Xu, C. , Ding, X. X. , Zhu, S. D. , Chen, H. N. , & Qi, D. M. (2015). Synthesis of fragrance/silica nanocapsules through a sol‐gel process in miniemulsions and their application as aromatic finishing agents. Colloid and Polymer Science, 293, 1129–1139. 10.1007/s00396-015-3502-2 - DOI
    1. Ciriminna, R. , & Pagliaro, M. (2013). Sol‐gel microencapsulation of odorants and flavors: Opening the route to sustainable fragrances and aromas. Chemical Society Reviews, 42, 9243–9250. 10.1039/c3cs60286a - DOI - PubMed
    1. Cunha, D. , Yahia, M. B. , Hall, S. , Miller, S. R. , Chevreau, H. , Elkaïm, E. , … Serre, C. (2013). Rationale of drug encapsulation and release from biocompatible porous metal−organic frameworks. Chemistry of Materials, 25, 2767–2776. 10.1021/cm400798p - DOI

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