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Case Reports
. 2020 Apr 8:2020:6970823.
doi: 10.1155/2020/6970823. eCollection 2020.

Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Hadjkacem Faten  1 , Ghorbel Dorra  1 , Charfi Slim  2 , Safi Wajdi  1 , Charfi Nadia  1 , Chaabene Kais  3 , Boudawara Tahia  2 , Abid Mohamed  1
Affiliations
Case Reports

Ovarian Steroid Cell Tumor (Not Otherwise Specified): A Case Report of Ovarian Hyperandrogenism

Hadjkacem Faten et al. Case Rep Oncol Med. .

Abstract

Steroid cell tumors (SCTs) (not otherwise specified (NOS)) are rare sex cord-stromal tumors of the ovary. These are associated with hormonal disturbances resulting in menstrual bleeding patterns and androgenic effects. We report the case of a 36-year-old female presented with hirsutism, signs of virilization, and elevated androgen levels. Transvaginal ultrasound showed a solid-appearing right ovarian mass. She underwent fertility-sparing surgery with a laparoscopic left oophorectomy. Histological examination showed a benign steroid cell tumor, NOS. These tumors often small can then present a problem of positive diagnosis responsible for a delay in the diagnosis.

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Conflict of interest statement

The authors report no conflicts of interest.

Figures

Figure 1
Figure 1
Lobulated mass of the ovary with yellow-orange cut surface.
Figure 2
Figure 2
A diffuse tumor cell proliferation with fibrous septa (hematoxylin eosin 40x).
Figure 3
Figure 3
Tumor cells were polygonal with granular eosinophilic cytoplasm. They were intermingled with some large pale and vacuolated cells (hematoxylin eosin 40x).
Figure 4
Figure 4
(a) Oil-red-O stain demonstrates numerous lipid droplets (40x); (b) positive staining of tumor cells for inhibin (400x); (c) positive staining of tumor cells for CD56 (400x); (d) positive staining of tumor cells for Melan A (400x).
See this image and copyright information in PMC

References

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