Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Jun;46(6):1124-1126.
doi: 10.1007/s00134-020-06057-8. Epub 2020 Apr 23.

Time to consider histologic pattern of lung injury to treat critically ill patients with COVID-19 infection

Collaborators, Affiliations
Comment

Time to consider histologic pattern of lung injury to treat critically ill patients with COVID-19 infection

Marie-Christine Copin et al. Intensive Care Med. 2020 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

All the authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
COVID-19 pulmonary histological findings. a Infiltration of alveolar walls by numerous lymphocytes and edema (thin arrow). Type 2 pneumocyte hyperplasia with cytologic atypia (thick arrow). HES × 200. b Intraluminal loose connective tissue (thin arrow) within bronchiole (bronchiolitis obliterans). Bronchiolar epithelium, thick arrow HES × 200. c Organizing pneumonia (thin arrow) within the alveolar ducts coexisting with fibrin balls (thick arrow). HES × 200. d Endothelial damage: cytoplasmic vacuolization of endothelial cells (arrow). HES × 200

Comment on

References

    1. Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, Camporota L. COVID-19 pneumonia: different respiratory treatment for different phenotypes? Intensive Care Med. 2020 doi: 10.1007/s00134-020-06033-2. - DOI - PMC - PubMed
    1. Beasley MB, Franks TJ, Galvin JR, Gochuico B, Travis WD. Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage. Arch Pathol Lab Med. 2002;126(9):1064–1070. - PubMed
    1. Hwang DM, Chamberlain DW, Poutanen SM, Low DE, Asa SL, Butany J. Pulmonary pathology of severe acute respiratory syndrome in Toronto. Mod Pathol. 2005;18(1):1–10. doi: 10.1038/modpathol.3800247. - DOI - PMC - PubMed
    1. Wang Y, Li Y, Wang Q, Zhang L, Li J, Zhu C. Acute fibrinous and organizing pneumonia: a case report. Medicine (Baltimore) 2019;98(8):e14537. doi: 10.1097/MD.0000000000014537. - DOI - PMC - PubMed
    1. López-Cuenca S, Morales-García S, Martín-Hita A, Frutos-Vivar F, Fernández-Segoviano P, Esteban A. Severe acute respiratory failure secondary to acute fibrinous and organizing pneumonia requiring mechanical ventilation: a case report and literature review. Respir Care. 2012;57(8):1337–1341. doi: 10.4187/respcare.01452. - DOI - PubMed

LinkOut - more resources