Bile acids mediate signaling between microbiome and the immune system
- PMID: 32329090
- DOI: 10.1111/imcb.12332
Bile acids mediate signaling between microbiome and the immune system
Comment on
-
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells.Nature. 2020 May;581(7809):475-479. doi: 10.1038/s41586-020-2193-0. Epub 2020 Apr 15. Nature. 2020. PMID: 32461639 Free PMC article.
References
-
- Smith PM, Howitt MR, Panikov N, et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 2013; 341: 569-573.
-
- Arpaia N, Campbell C, Fan X, et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 2013; 504: 451-455.
-
- Furusawa Y, Obata Y, Fukuda S, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells. Nature 2013; 504: 446-450.
-
- Campbell C, McKenney PT, Konstantinovsky D, et al. Bacterial metabolism of bile acids promotes peripheral Treg cell generation. Nature. https://doi.org/10.1038/s41586-020-2193-0
-
- Hang S, Paik D, Yao L, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature 2019; 576: 143-148.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
