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. 2020 Aug;47(8):3614-3620.
doi: 10.1002/mp.14197. Epub 2020 Jun 15.

Dosimetry evaluation of the GammaPod stereotactic radiosurgery device based on established AAPM and IAEA protocols

Stewart J Becker  1 , Wesley S Culberson  2 , Yannick Poirier  1 , Yildirim Mutaf  1 , Ying Niu  3 , Elizabeth M Nichols  1 , Byongyong Yi  1
Affiliations

Dosimetry evaluation of the GammaPod stereotactic radiosurgery device based on established AAPM and IAEA protocols

Stewart J Becker et al. Med Phys. 2020 Aug.

Abstract

Purpose: The GammaPod is a novel dedicated prone breast stereotactic radiosurgery (SRS) device recently developed at the University of Maryland Medical Center. This device utilizes multiple rotating Co-60 sources to create highly conformal dose distributions for breast treatments, including boosts, partial breast irradiation, or presurgery SRS. However, due to its small field sizes and nonstandard geometry, existing calibration protocols cannot be directly applied. In this study, we adapt and implement the American Association of Physicists in Medicine Task Group 21 (TG-21) and International Atomic Energy Agency (IAEA) Technical Report Series 483 (TRS 483) protocols for reference dose measurements for the GammaPod. This represents the first published dosimetric investigation GammaPod and is meant to serve as a reference to future users commissioning and calibrating these devices.

Methods: Reference dose measurements were performed following the TG-21/IAEA TRS 483 protocols using an ADCL-calibrated Exradin A1SL thimble chamber in a polymethyl methacrylate (PMMA) breast-mimicking phantom. Monte Carlo calculations and measurements were also performed in water to determine chamber-specific k PMMA Q m s r , Q 0 f msr , f ref quality conversion factor converting reference field size (fref ) to machine-specific field sizes (fmsr ) (25-mm) as well as k PMMA f clin , f msr , the conversion factor from the (fmsr ) to the clinical field size (fclin ) (15mm). Verification was performed using the thermoluminescent dosimeter remote monitoring service from the Imaging and Radiation Oncology Core (IROC) in Houston, TX.

Results: The (fref ) to (fmsr ) chamber-specific factor k PMMA Q m s r , Q 0 f msr , f ref was 0.992 while the (fmsr ) to (fclin ) chamber-specific k PMMA f clin , f msr factor was 1.014. The radiation absorbed dose to water measured in the PMMA phantom based on the TG-21/IAEA TRS 483 formalism agreed with IROC values to within 1% and 2% for the 25- and 15-mm collimators, respectively.

Conclusion: We successfully implemented the TG-21 and TRS 483 reference dosimetry protocols for the GammaPod. These results show agreement between measurements performed with different reference dosimetry protocols and independent thermoluminescent measurements.

Keywords: IAEA TRS 483; TG-21; breast; cancer; stereotactic radiosurgery.

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References

REFERENCES

    1. Becker S, Sabouri P, Niu Y, et al. Commissioning and acceptance guide for the GammaPod. Phys Med Biol. 2019;64(20):205021.
    1. Yu CX, Shao X, Zhang J, et al. GammaPod-a new device dedicated for stereotactic radiotherapy of breast cancer. Med Phys. 2013;40(5):051703.
    1. Mutaf YD, Zhang J, Yu CX, et al. Dosimetric and geometric evaluation of a novel stereotactic radiotherapy device for breast cancer: the GammaPod. Med Phys. 2013;40(4):041722.
    1. Becker SJ, Niu Y, Mutaf Y, et al. Development and validation of a comprehensive patient-specific quality assurance program for a novel stereotactic radiation delivery system for breast lesions. J Appl Clin Med Phys. 2019;20(12):138-148.
    1. Almond PR, Biggs PJ, Coursey BM, et al. AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys. 1999;26(9):1847-1870.

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