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. 2020 Apr 22;12(4):1030.
doi: 10.3390/cancers12041030.

PET-FDG: Impetus

Cristina Nanni  1
Affiliations

PET-FDG: Impetus

Cristina Nanni. Cancers (Basel). .

Abstract

The International Myeloma Working Group (IMWG)recommends FDG PET/CT (Fluoro-Deoxy-glucose Positron Emission Tomography/Computed Tomography) as the gold standard imaging modality for initial evaluation and response to therapy assessment in multiple myeloma. In fact, FDG PET/CT, provides multiple useful indexes to risk-stratify patients and has significant prognostic value. However, multiple myeloma remains a complex disease to interpret on imaging. The Italian myeloma criteria for PET use (IMPeTUs) were proposed to standardize FDG PET/CT reading in multiple myeloma. In this communication an overview on IMPeTUs is provided as well as some examples of application.

Keywords: FDG; IMPeTUs; PET; interpretation criteria; multiple myeloma.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
(A) MIP (Maximum Intensity Projection); (B) PET (Positron Emission Tomography) sagittal cut to highlight the bone marrow diffuse uptake; (C) CT (Computed Tomography) sagittal cut. No abnormal uptake is present.
Figure 2
Figure 2
(A) MIP; (B) PET sagittal cut; (C) CT sagittal cut; (D–I) fused images and CT axial cut on different focal lesions. There are at least three focal hot spots with no underlying lytic lesions (D: vertebra, F: sacrum, H: right rib).
Figure 3
Figure 3
(A) MIP; (B) PET sagittal cut; (C) fused images axial cut; (D) CT axial cut. There are at least four focal hot spots with lytic lesions underlying and a subcutaneous lesion in the left thorax (C).
Figure 4
Figure 4
(A) MIP; (B) PET sagittal cut; (C) CT sagittal cut. There is a diffuse and severe bone marrow uptake in limbs, pelvis and spine.
Figure 5
Figure 5
(A) MIP; (B) PET sagittal cut; (C) fused images axial cut; (D) CT axial cut; (E) fused images axial cut. There is a lytic lesion in the sternum involving surrounding tissues (C) and a cold lytic lesion in the right bony pelvis (E).
See this image and copyright information in PMC

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