Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: A retrospective study

Abstract

Background: COVID-19 is spreading globally. This study aims to evaluate the clinical characteristics and outcomes of pregnant women confirmed with COVID-19 to provide reference for clinical work.

Methods: The clinical features and outcomes of 10 pregnant women confirmed with COVID-19 at Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, a tertiary- care teaching hospital in Hubei province, Wuhan, China from January 23 to February 23, 2020 were retrospectively analyzed.

Results: All the 10 observed pregnant women including 9 singletons and 1 twin were native people in Wuhan. All of them were diagnosed mild COVID-19, and none of the patients developed severe COVID-19 or died. Among the 10 patients, two patients underwent vaginal delivery, two patients underwent intrapartum cesarean section, and the remaining six patients underwent elective cesarean section. All of 10 patients showed lung abnormalities by pulmonary CT images after delivery. Their eleven newborns were recorded and no neonatal asphyxia was observed.

Conclusions: Pulmonary CT screening on admission may be necessary to reduce the risk of nosocomial transmission of COVID-19 during the outbreak period. And COVID-19 is not an indication of cesarean section.

Keywords: COVID-19; Infection; Public health; pregnant women; pulmonary CT screening.

Fig. 1

Chest CT images, showing bilateral lower lung cord from patient 1.

Fig. 2

Chest CT images, showing ground-glass nodule on the right upper lobe from patient 2.

Fig. 3

Chest CT images, showing spotted slightly denser shadows scattered on the right lower lobe from patient 3.

Fig. 4

Chest CT images, showing patchy shadows of bilateral lungs, thickened dorsal pleura from patient 4.

Fig. 5

Chest CT images, showing a little patchy shadow on the dorsal side of bilateral lower lungs and a little pleural effusion from patient 5.

Fig. 6

Chest CT images, showing a few patchy shadows on bilateral lungs and a small amount of pleural effusion on both sides from patient 6.

Fig. 7

Chest CT images, showing ground-glass density nodules on the left from patient 7.

Fig. 8

Chest CT images, showing patches near the pleura, bilateral pleural effusion from patient 8.

Fig. 9

Chest CT images, showing ground glass and patch shadows scattered on the bilateral lungs, especially obvious on the right, the bronchi dilation in the right lobe, a little pleural effusion on both sides from patient 9.

Fig. 10

Chest CT images, showing patchy ground glass shadow of the left upper lobe with high density of some lesions from patient 10.