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. 2020 May 6;21(5):e50521.
doi: 10.15252/embr.202050521. Epub 2020 Apr 26.

The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?

Jacob Beal  1 , Angel Goñi-Moreno  2   3 , Chris Myers  4 , Ariel Hecht  5 , María Del Carmen de Vicente  6 , Maria Parco  7 , Markus Schmidt  8 , Kenneth Timmis  9 , Geoff Baldwin  10 , Steffi Friedrichs  11 , Paul Freemont  10 , Daisuke Kiga  12 , Elena Ordozgoiti  13 , Maja Rennig  14 , Leonardo Rios  15 , Kristie Tanner  16 , Víctor de Lorenzo  17 , Manuel Porcar  18
Affiliations

The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?

Jacob Beal et al. EMBO Rep. .

Abstract

Synthetic biology needs to adopt sound scientific and industry-like standards in order to achieve its ambitious goals of efficient and accurate engineering of biological systems.

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Figures

Figure 1
Figure 1. Adoption curve of/for biological standards
Illustrative examples of the position of SynBio standards along the technology adoption curve: SynBio standards are largely still in the innovator phase but with a few examples having progressed to the early adopters or early majority segments. SBOL, Synthetic Biology Open Language; SEVA, Standard European Vector Architecture; MoClo, modular cloning.
See this image and copyright information in PMC

References

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    1. Beal J, Haddock‐Angelli T, Farny N, Reggberg R (2018) Time to get serious about measurement in synthetic biology. Trends Biotechnol 36: 869–871 - PubMed
    1. Vilanova C, Porcar M (2014) IGEM 2.0–refoundations for engineering biology. Nat Biotechnol 32: 420–424 - PubMed
    1. Carr SB, Beal J, Densmore DM (2017) Reducing DNA context independence in bacterial promoters. PLoS ONE 12: e0176013 - PMC - PubMed
    1. de Lorenzo V, Schmidt M (2018) Biological standards for the knowledge‐Based BioEconomy: what is at stake. New Biotechnol 40: 170–180 - PubMed

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