Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Apr 27;15(4):e0230481.
doi: 10.1371/journal.pone.0230481. eCollection 2020.

Association between sleep duration and osteoarthritis and their prevalence in Koreans: A cross-sectional study

Yongkyu Cho  1 , Boyoung Jung  2 , Yoon Jae Lee  3 , Me-Riong Kim  1 , Eun-Jung Kim  4 , Won-Suk Sung  4 , In-Hyuk Ha  3
Affiliations

Association between sleep duration and osteoarthritis and their prevalence in Koreans: A cross-sectional study

Yongkyu Cho et al. PLoS One. .

Abstract

Objective: To determine the association of radiological and symptomatic osteoarthritis with sleep duration in a representative sample of the Korean population.

Methods: Using data from the national cross-sectional fifth Korea National Health and Nutrition Examination Survey 2010-2012. Of the 16,528 participants in KNHANES-V, 8,918 were adults aged≥ 50 years who had completed the survey questions on sleep duration and osteoarthritis, and had diagnostic X-ray results. We evaluated the association between sleep duration as the primary predictor for osteoarthritis involving the hip, knee, and spinal joints. A complex sample logistic regression analysis was performed to adjust for the covariates.

Results: Proportions of participants with total daily sleep duration of ≤6 hours, 7-8 hours, and ≥9 hours were 47.1%, 45.2, and 7.7%, respectively. The rate of osteoarthritis diagnoses in the ≤6 hours, 7-8 hours, and ≥9 hours of sleep duration groups was 24.1%, 17.6%, and 21.8%, respectively (p <0.0001). The odds ratios (OR) were significantly higher in the ≤6 hours of sleep group than in the 7-8 hours of sleep group (OR, 1.20; 95% confidence interval [CI], 1.03-1.39; p = 0.02), but no significant difference in the ≥9 hours of sleep group was found after adjusting the confounding variables. When we compared knee joint pain (Numeric Rating Scale 0 versus 1-10) in participants with grade 2-4 Kellgren-Lawrence (KL) classification after adjusting these same confounding variables, the ≤6 hours of sleep group (OR, 1.32; 95% CI, 1.10-1.58) and the ≥9 hours of sleep group (OR, 1.41; 95% CI, 1.03-1.95) showed significantly higher ORs.

Conclusion: This study confirmed the significant association between sleep duration and osteoarthritis in adults aged ≥50 years. Participants' positive for both radiological (KL grade ≥2) and symptomatic osteoarthritis showed a strong association between knee joint pain and not enough sleep duration.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Subjects’ flow diagram.
See this image and copyright information in PMC

References

    1. Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis care & research. 2012;64(4):465–74. - PubMed
    1. Wu Q, Zhu M, Rosier RN, Zuscik MJ, O’Keefe RJ, Chen D. β‐catenin, cartilage, and osteoarthritis. Annals of the New York academy of sciences. 2010;1192(1):344–50. - PMC - PubMed
    1. Kim H-R, Kim E-J. Prevalence of osteoarthritis and its affecting factors among a Korean population aged 50 and over. Journal of Korean public health nursing. 2013;27(1):27–39.
    1. Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, et al. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Annals of the rheumatic diseases. 2014;73(7):1323–30. 10.1136/annrheumdis-2013-204763 - DOI - PubMed
    1. Montero A, Mulero J-F, Tornero C, Guitart J, Serrano M. Pain, disability and health-related quality of life in osteoarthritis—joint matters: an observational, multi-specialty trans-national follow-up study. Clinical rheumatology. 2016;35(9):2293–305. 10.1007/s10067-016-3248-3 - DOI - PubMed