Anti-VEGF and Retinal Dystrophies

Abstract

The therapeutic approach based on anti-vascular endothelial growth factor (anti-VEGF) molecules can be used to treat two important complications of retinal dystrophies: choroidal neovascularization and macular edema. The macular involvement in retinal dystrophies can lead to further visual deterioration in patients at a young age and already affected by functional limitations. The study reports the effect of anti-VEGF treatment in several subforms of retinal dystrophies, critically discussing advantages and limitations.

Keywords: Choroidal neovascularization; anti-VEGF; best vitelliform macular dystrophy; macular edema retinitis pigmentosa; pattern dystrophy; stargardt disease.