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. 2020 Aug:78:143-146.
doi: 10.1016/j.jocn.2020.04.095. Epub 2020 Apr 25.

Plasma copeptin levels in patients with multiple sclerosis

Mesrure Koseoglu  1 , Serkan Ozben  2 , Gokcen Gozubatik-Celik  1 , Mesude Tutuncu  1 , Ertan Kucuksayan  3 , Aysegul Hanikoğlu  3 , Dilek Atakli  1 , Tomris Ozben  3
Affiliations

Plasma copeptin levels in patients with multiple sclerosis

Mesrure Koseoglu et al. J Clin Neurosci. 2020 Aug.

Abstract

We compared copeptin levels in relapsing-remitting multiple sclerosis (RRMS) patients with controls and investigated how plasma copeptin levels were changed with the disease period. Thirty patients with RRMS without a prior attack in the last twelve months, and 19 RRMS patients with a clinical acute attack and 30 healthy individuals were included into the study. Copeptin levels were significantly higher in all RRMS patient groups than healthy controls. Plasma copeptin levels were higher in patients in remission period compared with relapse period of 19 RRMS patients with an acute attack. We consider copeptin can be used as a potential biomarker for RRMS.

Keywords: Antidiuretic hormone; Copeptin; Multiple sclerosis.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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