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Case Reports
. 2020 Apr 28;5(6):940-945.
doi: 10.1016/j.ekir.2020.04.017. eCollection 2020 Jun.

Acute Kidney Injury Due to Collapsing Glomerulopathy Following COVID-19 Infection

Yonatan Peleg  1 , Satoru Kudose  2 , Vivette D'Agati  2 , Eric Siddall  1 , Syeda Ahmad  1 , Thomas Nickolas  1 , Sergey Kisselev  1 , Ali Gharavi  1 , Pietro Canetta  1
Affiliations
Case Reports

Acute Kidney Injury Due to Collapsing Glomerulopathy Following COVID-19 Infection

Yonatan Peleg et al. Kidney Int Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Renal biopsy. Representative light microscopy demonstrates global collapse of the glomerular capillary loops accompanied by hyperplasia of overlying glomerular epithelial cells, many of which contain abundant eosinophilic intracytoplasmic protein droplets (a,b, Jones methenamine silver stain, original magnification ×400). Acute tubular injury involves many cortical tubules, accompanied by interstitial edema and mild interstitial mononuclear inflammatory infiltrates (c, hematoxylin-eosin stain, original magnification ×400). Scattered proximal tubules contain abundant intracytoplasmic periodic acid–Schiff–positive protein resorption droplets (d, periodic acid–Schiff stain, original magnification ×400).
Figure 2
Figure 2
Severe acute respiratory syndrome–novel Coronavirus 2 (SARS-CoV-2) in situ hybridization. A representative glomerulus and the adjacent cortical tubular epithelial cells show negative staining for SARS-CoV-2 by in situ hybridization (original magnification ×400).
See this image and copyright information in PMC

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References

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