Neurological Implications of COVID-19 Infections
- PMID: 32346843
- PMCID: PMC7188454
- DOI: 10.1007/s12028-020-00978-4
Neurological Implications of COVID-19 Infections
Abstract
The magnitude of the COVID-19 pandemic will result in substantial neurological disease, whether through direct infection (rare), para-infectious complications (less rare), or critical illness more generally (common). Here, we raise the importance of stringent diagnosis and data collection regarding neurological complications of COVID-19; we urge caution in the over-diagnosis of neurological disease where it does not exist, but equally strongly encourage the concerted surveillance for such conditions. Additional to the direct neurological complications of COVID-19 infection, neurological patients are at risk of harm from both structural limitations (such as number of intensive care beds), and a hesitancy to treat with certain necessary medications given risk of nosocomial COVID-19 infection. We therefore also outline the specific management of patients with neuroinflammatory diseases in the context of the pandemic. This article describes the implications of COVID-19 on neurological disease and advertises the Neurocritical Care Society's international data collection collaborative that seeks to align data elements.
Keywords: Acute disseminated encephalomyelitis; COVID-19; Encephalitis; Guillain–Barré syndrome.
Conflict of interest statement
The authors declare that they have no conflicts of interest.
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References
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- Mao L, Wang M, Chen S et al. 2020. Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study. medRxiv. 10.1101/2020.02.22.20026500.
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- Li Y, Wang M, Zhou Y et al. Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study (3/3/2020). Available at SSRN: https://ssrn.com/abstract=3550025 or 10.2139/ssrn.3550025. - DOI - PMC - PubMed
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