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. 2020 Sep;27(9):955-958.
doi: 10.1111/jvh.13308. Epub 2020 May 22.

Response to direct-acting antivirals for hepatitis C treatment in vertically HIV/HCV co-infected patients

Itzíar Carrasco  1   2 , Talía Sainz  3 , Marie Antoinette Frick  4 , Santiago Jiménez de Ory  1 , Claudia Fortuny  5 , Joaquin Burgos  4 , Marta Montero  6 , César Gavilán  7 , María Dolores Falcón  8 , José Antonio Couceiro  9 , José Ignacio Bernardino  3 , Otilia Bisbal  10 , Carmelo Guerrero  11 , María Teresa Aldámiz-Echevarría  1 , Juan Berenguer  1 , María Luisa Navarro  1   2 ; the Pediatric National AIDS Research Network of Spain (CoRISpe) integrated in the Translational Research Network in Pediatric Infectious Diseases (RITIP)
Affiliations

Response to direct-acting antivirals for hepatitis C treatment in vertically HIV/HCV co-infected patients

Itzíar Carrasco et al. J Viral Hepat. 2020 Sep.

Abstract

Direct-acting antivirals (DAAs) for HCV treatment have improved tolerance and efficacy among adults, but experience in vertical transmission is scarce. In our vertically HIV/HCV co-infected youth cohort of 58 patients, DAA achieved excellent rates of cure among naïve and pretreated individuals. Treating vertically infected seems important as 29.6% displayed advanced fibrosis at treatment initiation.

Keywords: HCV treatment; VIH/VHC co-infection; children and adolescents; direct-acting antivirals; vertical transmission.

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References

REFERENCES

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