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Review
. 2020 May 1;59(Suppl 3):iii95-iii100.
doi: 10.1093/rheumatology/kez599.

Childhood vasculitis

Seza Ozen  1 , Erdal Sag  1
Affiliations
Review

Childhood vasculitis

Seza Ozen et al. Rheumatology (Oxford). .

Abstract

Vasculitis is a challenging disease for paediatricians. Certain vasculitides are quite common in children whereas others are much rarer compared with adults. The most common vasculitides in childhood are IgA-associated vasculitis (Henoch-Schönlein purpura) and Kawasaki disease, which are usually self-limiting vasculitides although children do develop complications as a result. We now have much better knowledge of how to manage these patients and prevent the deleterious complications. This review provides an up-to-date discussion on childhood vasculitides, including diagnosis, treatment and follow-up strategies, together with a comparison with vasculitides in adults. It also discusses the newly defined monogenic vasculitides that often present during early childhood.

Keywords: IgA vasculitis; Kawasaki; PAN; SAVI; childhood vasculitis; deficiency of ADA2.

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