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. 2020 Jun 15;201(12):1560-1564.
doi: 10.1164/rccm.202004-1163LE.

Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19: A Cohort Study

David R Ziehr  1   2 , Jehan Alladina  1 , Camille R Petri  1   2 , Jason H Maley  1   2 , Ari Moskowitz  2 , Benjamin D Medoff  1 , Kathryn A Hibbert  1 , B Taylor Thompson  1 , C Corey Hardin  1
Affiliations

Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19: A Cohort Study

David R Ziehr et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Respiratory indices during the first 5 days of mechanical ventilation. Respiratory indices, including the PaO2:FiO2 ratio, plateau pressure (Pplat), positive end-expiratory pressure (PEEP), and static compliance of the respiratory system (CstatRS), were obtained daily in intubated patients with coronavirus disease (COVID-19) respiratory failure. The number of patients with recorded values is shown below the x-axis. The solid line indicates the median value.
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References

    1. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020;323:1574–1581. - PMC - PubMed
    1. Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Lancet Respir Med 2020;pii:S2213-2600(20)30079-5. - PMC - PubMed
    1. Bhatraju PK, Ghassemieh BJ, Nichols M, Kim R, Jerome KR, Nalla AK, et al. Covid-19 in critically ill patients in the Seattle region - case series. N Engl J Med. [online ahead of print] 30 Mar 2020; DOI: 10.1056/NEJMoa2004500. - PMC - PubMed
    1. Gattinoni L, Coppola S, Cressoni M, Busana M, Rossi S, Chiumello D. Covid-19 does not lead to a “typical” acute respiratory distress syndrome. Am J Respir Crit Care Med. [online ahead of print] 30 Mar 2020; DOI: 10.1164/rccm.202003-0817LE. - PMC - PubMed
    1. Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med. [online ahead of print] 14 Apr 2020; DOI: 10.1007/s00134-020-06033-2. - PMC - PubMed

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