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Comment
. 2020 Apr 15:11:337.
doi: 10.3389/fphys.2020.00337. eCollection 2020.

Response: Commentary: Neuromuscular and Muscle Metabolic Functions in MELAS Before and After Resistance Training: A Case Study

Massimo Venturelli  1 , Federico Ruzzante  1 , Federica Villa  1 , Doriana Rudi  1 , Cantor Tarperi  1 , Chiara Milanese  1 , Valentina Cavedon  1 , Cristina Fonte  1 , Alessandro Picelli  1 , Nicola Smania  1 , Elisa Calabria  1 , Spiros Skafidas  1 , Stefania Fochi  1 , Maria Grazia Romanelli  1 , Gwenael Layec  2 , Federico Schena  1
Affiliations
Comment

Response: Commentary: Neuromuscular and Muscle Metabolic Functions in MELAS Before and After Resistance Training: A Case Study

Massimo Venturelli et al. Front Physiol. .
No abstract available

Keywords: MELAS; exercise; force; mitocondrial function; muscle mass; resistance training.

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Figures

Figure 1
Figure 1
Determination of the A3243G mutation in the mtDNA portion coding for tRNAleu(UUR). (A) DNA sequencing chromatogram for subject DNA product. The peak labeled with an arrow represented the presence of an adenine (A) in the 3243 region of the mtDNA gene. (B) Restriction enzyme analysis of PCR products. Lane 1,25 bp DNA ladder (Invitrogen); lane 2, normal control DNA product not digested; lane 3, normal control DNA product digested with ApaI; lane 4, patient DNA product not digested; lane 5, patient DNA product digested with ApaI.
Figure 2
Figure 2
Mitochondrial function analyzed in permeabilized PBMCs. Mitochondrial function was analyzed using a substrate inhibitor titration (SUIT) protocol and data of Flux Control Ratio (FCR) relative to ETS are reported for controls (CTRL) and PATIENT. The ROUTINE (A), LEAK (B), OXPHOS cI (PM, C), respiratory states and ETS coupling efficiency (1-L/E, D) were analyzed. Data are represented as mean ± SD. *P < 0.05.
See this image and copyright information in PMC

Comment on

References

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