Fluorescent metal-based complexes as cancer probes
- PMID: 32360103
- DOI: 10.1016/j.bmcl.2020.127219
Fluorescent metal-based complexes as cancer probes
Abstract
The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects.
Keywords: Anticancer probes; Fluorescence microscopy; Fluorescent probes; Metal complexes; Metal-based probes; Targeting; Theranostics.
Copyright © 2020 Elsevier Ltd. All rights reserved.
Conflict of interest statement
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Similar articles
-
Recent development of transition metal complexes with in vivo antitumor activity.J Inorg Biochem. 2017 Dec;177:276-286. doi: 10.1016/j.jinorgbio.2017.06.002. Epub 2017 Jun 16. J Inorg Biochem. 2017. PMID: 28641893 Review.
-
Phosphorescent heavy-metal complexes for bioimaging.Chem Soc Rev. 2011 May;40(5):2508-24. doi: 10.1039/c0cs00114g. Epub 2011 Jan 21. Chem Soc Rev. 2011. PMID: 21253643 Review.
-
Activity-Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image-Guided Surgery.Angew Chem Int Ed Engl. 2021 Aug 2;60(32):17268-17289. doi: 10.1002/anie.202009796. Epub 2021 Feb 25. Angew Chem Int Ed Engl. 2021. PMID: 32939923 Review.
-
Modified Indulines: From Dyestuffs to In Vivo Theranostic Agents.ACS Appl Mater Interfaces. 2021 Jul 7;13(26):30337-30349. doi: 10.1021/acsami.1c05933. Epub 2021 Jun 23. ACS Appl Mater Interfaces. 2021. PMID: 34159778
-
Biotinylated platinum(ii) metallacage towards targeted cancer theranostics.Chem Commun (Camb). 2020 Jul 28;56(60):8460-8463. doi: 10.1039/d0cc03824e. Chem Commun (Camb). 2020. PMID: 32583830
Cited by
-
ISAC Probe Tag Dictionary: Standardized Nomenclature for Detection and Visualization Labels Used in Cytometry and Microscopy Imaging.Cytometry A. 2021 Jan;99(1):103-106. doi: 10.1002/cyto.a.24224. Epub 2020 Sep 16. Cytometry A. 2021. PMID: 32881392 Free PMC article.
-
A Dipeptide-derived Dansyl Fluorescent Probe for the Detection of Cu2+ in Aqueous Solutions.J Fluoresc. 2023 Nov;33(6):2515-2521. doi: 10.1007/s10895-023-03274-4. Epub 2023 May 19. J Fluoresc. 2023. PMID: 37204534
-
A multiple acetal chalcone-BODIPY-based fluorescence: synthesis, physical property, and biological studies.Anal Bioanal Chem. 2021 Apr;413(9):2529-2541. doi: 10.1007/s00216-021-03208-8. Epub 2021 Mar 12. Anal Bioanal Chem. 2021. PMID: 33712915
-
N-Heterocyclic Carbene-Iridium Complexes as Photosensitizers for In Vitro Photodynamic Therapy to Trigger Non-Apoptotic Cell Death in Cancer Cells.Molecules. 2023 Jan 10;28(2):691. doi: 10.3390/molecules28020691. Molecules. 2023. PMID: 36677751 Free PMC article.
-
Metal-Based G-Quadruplex Binders for Cancer Theranostics.Pharmaceuticals (Basel). 2021 Jun 23;14(7):605. doi: 10.3390/ph14070605. Pharmaceuticals (Basel). 2021. PMID: 34201682 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical