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Review
. 2020 Jul 1;30(13):127219.
doi: 10.1016/j.bmcl.2020.127219. Epub 2020 Apr 28.

Fluorescent metal-based complexes as cancer probes

Andreia de Almeida  1 , Riccardo Bonsignore  2
Affiliations
Review

Fluorescent metal-based complexes as cancer probes

Andreia de Almeida et al. Bioorg Med Chem Lett. .

Abstract

The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects.

Keywords: Anticancer probes; Fluorescence microscopy; Fluorescent probes; Metal complexes; Metal-based probes; Targeting; Theranostics.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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