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. 2020 Sep;125(3):e280-e281.
doi: 10.1016/j.bja.2020.04.012. Epub 2020 Apr 18.

COVID-19 patients with respiratory failure: what can we learn from aviation medicine?

William Ottestad  1 , Signe Søvik  2
Affiliations

COVID-19 patients with respiratory failure: what can we learn from aviation medicine?

William Ottestad et al. Br J Anaesth. 2020 Sep.
No abstract available

Keywords: COVID-19; acute respiratory distress syndrome; aviation medicine; hypocapnia; hypocapnic hypoxia; hypoxaemia; respiratory failure.

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Figures

Figure 1
Fig 1
Relation between arterial oxygen saturations (SaO2) and arterial partial pressures of carbon dioxide (PaCO2) in eight volunteers breathing air in a hypobaric chamber at ambient pressure 42.1 kPa, corresponding to a pressure altitude of ∼22 000 ft. Inspiratory oxygen pressure is 7.5 kPa. The model predicts that an increase in PaCO2 from 2.5 to 4.5 kPa would decrease SaO2 from 87% to 50%. R2=0.88, P<0.001.
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