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Review
. 2020 Mar 27;6(2):87-97.
doi: 10.1016/j.cdtm.2020.02.003. eCollection 2020 Jun.

Recommended prophylactic and management strategies for severe acute respiratory syndrome coronavirus 2 infection in transplant recipients

Chun-Rong Ju  1 , Qiao-Yan Lian  1 , Jian-Heng Zhang  1 , Tao Qiu  2 , Zhi-Tao Cai  2 , Wen-Yang Jiang  3 , Jing Zhang  4 , Qin Cheng  5 , Gang Chen  6 , Ning Li  7 , Chun-Yan Wang  8 , Jian-Xing He  1
Affiliations
Review

Recommended prophylactic and management strategies for severe acute respiratory syndrome coronavirus 2 infection in transplant recipients

Chun-Rong Ju et al. Chronic Dis Transl Med. .

Abstract

Since December 2019, increasing attention has been paid to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Wuhan, China. SARS-CoV-2 primarily invades the respiratory tract and lungs, leading to pneumonia and other systemic disorders. The effect of SARS-CoV-2 in transplant recipients has raised significant concerns, especially because there is a large population of transplant recipients in China. Based on the current epidemic situation, this study reviewed publications on this virus and coronavirus disease 2019 (COVID-19), analyzed common features of respiratory viral pneumonias, and presented the currently reported clinical characteristics of COVID-19 in transplant recipients to improve strategies regarding the diagnosis and treatment of COVID-19 in this special population.

Keywords: Corona virus disease 2019; Novel coronavirus; Pneumonia; Recipients; Transplantation.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Imaging manifestation of a kidney transplant recipient infected with the COVID-19; female, 39 years old, 19 months after kidney transplant; moderate fever, dry cough and fatigue are the main symptoms of the patient.
Fig. 2
Fig. 2
Imaging manifestation of a HSCT recipient infected with the CMV pneumonia; male, 40 years old, 3 years after HSCT; fever, cough, fatigue and progressive shortness of breath are the main symptoms of the patient.
See this image and copyright information in PMC

References

    1. Bajema K.L., Oster A.M., McGovern O.L., 2019-CoV Persons under Investigation Team Persons evaluated for 2019 novel coronavirus – United States, January 2020. MMWR Morb Mortal Wkly Rep. 2020 Feb 14;69(6):166–170. doi: 10.15585/mmwr.mm6906e1. - DOI - PMC - PubMed
    1. WHO Statement Regarding Cluster of Pneumonia Cases in Wuhan, China. 2020 Jan 9. https://www.who.int/china/news/detail/09-01-2020-who-statement-regarding...
    1. Diagnosis and Treatment Scheme for Novel Coronavirus-infected Pneumonia (6th Trial Edition) National Health Commission of the PRC; 2020 Feb 18. http://yzs.satcm.gov.cn/zhengcewenjian/2020-02-19/13221.html
    1. Xu L.P., Wu D.P., Han M.Z. A review of hematopoietic cell transplantation in China: data and trends during 2008–2016. Bone Marrow Transplant. 2017;52:1512–1518. - PubMed
    1. Shi B.Y. The development status of organ transplantation in China – report on the annual meeting of the Chinese medical association on organ transplantation in 2018 (in Chinese) Organ Transpl. 2019;10:32–35.