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Case Reports
. 2020 Jul 15;2(9):1321-1325.
doi: 10.1016/j.jaccas.2020.04.023. Epub 2020 May 1.

Takotsubo Syndrome in the Setting of COVID-19

Anum S Minhas  1   2 , Paul Scheel  1 , Brian Garibaldi  3 , Gigi Liu  4 , Maureen Horton  3 , Mark Jennings  3 , Steven R Jones  1 , Erin D Michos  1   2 , Allison G Hays  1
Affiliations
Case Reports

Takotsubo Syndrome in the Setting of COVID-19

Anum S Minhas et al. JACC Case Rep. .

Abstract

A 58-year-old woman was admitted with symptoms of coronavirus disease-2019. She subsequently developed mixed shock, and an echocardiogram showed mid-distal left ventricular hypokinesis and apical ballooning, findings typical of stress, or takotsubo, cardiomyopathy. Over the next few days her left ventricular function improved, the further supporting the reversibility of acute stress cardiomyopathy. (Level of Difficulty: Beginner.).

Keywords: COVID-19; COVID-19, coronavirus disease-2019; ECG, electrocardiogram; LV, left ventricular; RV, right ventricular; STEMI, ST-segment elevation myocardial infarction; acute cardiac dysfunction; stress cardiomyopathy; takotsubo.

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Figures

None
Graphical abstract
Figure 1
Figure 1
Initial Electrocardiogram
Figure 2
Figure 2
Strain Imaging on Initial Echocardiogram ANT = anterior; APLAX = apical long axis; AVC = aortic valve closure; CH = chamber; G = global; GS = global strain; HR = heart rate; INF = inferior; LAT = lateral; POST = posterior; PSD = peak systolic dispersion; SEPT = septal; SL = strain length.
Figure 3
Figure 3
Strain Imaging on Repeat Echocardiogram Abbreviations as in Figure 2.
Figure 4
Figure 4
Follow-Up Electrocardiogram
See this image and copyright information in PMC

References

    1. Zhou F., Yu T., Du R. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–1062. - PMC - PubMed
    1. Wang D., Hu B., Hu C. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061. - PMC - PubMed
    1. Inciardi R.M., Lupi L., Zaccone G. Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020 Mar 27 [E-pub ahead of print] - PMC - PubMed
    1. Templin C., Ghadri J.R., Diekmann J. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373:929–938. - PubMed
    1. Minhas A.S., Hughey A.B., Kolias T.J. Nationwide trends in reported incidence of takotsubo cardiomyopathy from 2006 to 2012. Am J Cardiol. 2015;116:1128–1131. - PubMed

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