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Review
. 2020 May;33(3):286-296.
doi: 10.1111/sdi.12881. Epub 2020 May 4.

When ESKD complicates the management of pain

Manisha Jhamb  1 , Laura Tucker  2 , Jane Liebschutz  3
Affiliations
Review

When ESKD complicates the management of pain

Manisha Jhamb et al. Semin Dial. 2020 May.

Abstract

Pain is one of the most common symptoms reported by patients with end-stage kidney disease (ESKD) and negatively impacts their health-related quality of life (HRQOL), dialysis adherence, healthcare utilization, and mortality. There are a number of patient-related and health system-related barriers that make it very challenging to treat pain in these patients. Moreover, the limited availability of efficacious and safe nonopiate analgesic options has led to over-use of opioids in this population. We propose a framework for pain assessment and tailored treatment using nonpharmacological and pharmacological approaches to optimize pain management and opioid use. Additionally, we recommend system-level changes to improve care coordination and pain management in ESKD patients.

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Conflict of interest statement

CONFLICT OF INTEREST

None.

Figures

FIGURE 1
FIGURE 1
Framework for designing approaches to improve pain management in patients with end-stage kidney disease
See this image and copyright information in PMC

References

    1. Abdel-Kader K, Unruh ML, Weisbord SD. Symptom burden, depression, and quality of life in chronic and end-stage kidney disease. Clin J Am Soc Nephrol. 2009;4(6):1057–1064. - PMC - PubMed
    1. Davison SN. Pain in hemodialysis patients: prevalence, cause, severity, and management. Am J Kidney Dis. 2003;42(6):1239–1247. - PubMed
    1. Jhamb M, Abdel-Kader K, Yabes J, et al. Comparison of fatigue, pain, and depression in patients with advanced kidney disease and cancer-symptom burden and clusters. J Pain Symptom Manage. 2019;57(3):566–575 e563. - PMC - PubMed
    1. Claxton RN, Blackhall L, Weisbord SD, Holley JL. Undertreatment of symptoms in patients on maintenance hemodialysis. J Pain Symptom Manage. 2010;39(2):211–218. - PubMed
    1. Jhamb M, Abdel-Kader K, Yabes J, et al. Comparison of fatigue, pain and depression in patients with advanced kidney disease and cancer - symptom burden and clusters. J Pain Symptom Manage. 2018. - PMC - PubMed