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Review
. 2020 Feb 15;11(2):4005-4012.
doi: 10.19102/icrm.2020.110205. eCollection 2020 Feb.

Permanent His-bundle Pacing in Pediatrics and Congenital Heart Disease

Affiliations
Review

Permanent His-bundle Pacing in Pediatrics and Congenital Heart Disease

Shannon Lyon et al. J Innov Card Rhythm Manag. .

Abstract

Permanent His-bundle pacing has been gaining popularity in the adult population requiring cardiac resynchronization therapy. Initial procedural challenges are being overcome, and this method of pacing has been shown to improve left ventricular function and heart failure symptoms secondary to ventricular dyssynchrony. Though the etiologies of ventricular dyssynchrony may differ in children and those with congenital heart disease than in adults with structurally normal hearts, His-bundle pacing may also be a preferred option in these groups to restore more physiologic electric conduction and improve ventricular function. We present a review of the current literature and suggested directions involving deploying permanent His-bundle pacing in the pediatric and congenital heart disease population.

Keywords: Adult congenital heart disease; His-bundle pacing; congenital heart disease; pediatric cardiology.

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Figures

Figure 1:
Figure 1:
A: Anteroposterior chest radiograph showing lead placement in a dual-chamber transvenous pacing system in a structurally normal heart. B: Lateral chest radiograph showing lead placement in a dual-chamber transvenous pacing system in a structurally normal heart.
Figure 2:
Figure 2:
A: Anteroposterior chest radiograph showing lead placement of a bipolar dual-chamber epicardial pacing system in a structurally normal heart. B: Lateral chest radiograph showing lead placement of a bipolar dual-chamber epicardial pacing system in a structurally normal heart.
Figure 3:
Figure 3:
A: Selective His-bundle pacing in a patient with a structurally normal heart. B: Nonselective His-bundle pacing in a patient with LTGA. C: RV pacing in a structurally normal heart with a resultant LBBB pattern.
Figure 4:
Figure 4:
A: Anteroposterior chest radiograph showing lead placement in a His-bundle pacing system in a patient with a structurally normal heart. B: Lateral chest radiograph showing lead placement in a His-bundle pacing system in a patient with a structurally normal heart.
Figure 5:
Figure 5:
A: Anteroposterior chest radiograph showing lead placement in a His-bundle pacing system in a patient with LTGA. B: Lateral chest radiograph showing lead placement in a His-bundle pacing system in a patient with LTGA.

References

    1. Sweeney MO, Hellkamp AS, Ellenbogen KA, et al. Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction. Circulation. 2003;107(23):2932–2937. [CrossRef] [PubMed] - DOI - PubMed
    1. Little WC, Reeves RC, Arciniegas J, Katholi RE, Rogers EW. Mechanism of abnormal interventricular septal motion during delayed left ventricular activation. Circulation. 1982;65(7):1486–1491. [CrossRef] [PubMed] - DOI - PubMed
    1. Shimony A. Beneficial effects of RV non-apical vs apical pacing: a systematic review and meta-analysis or randomized-controlled trials. Europace. 2012;14(1):81–91. [CrossRef] [PubMed] - DOI - PubMed
    1. Sharma PS, Ellenbogen KA, Trohman RG. Permanent his bundle pacing: the past, present, and future. J Cardiovasc Electrophysiol. 2017;28(4):458–465. [CrossRef] [PubMed] - DOI - PubMed
    1. Zhang XH, Chen H, Siu CW, et al. New-onset heart failure after permanent right ventricular apical pacing in patients with acquired high-grade atrioventricular block and normal left ventricular function. J Cardiovasc Electrophysiol. 2008;19(2):136–141. [CrossRef] [PubMed] - DOI - PubMed

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