Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

doi:10.1097/HJH.0000000000002472

Comment

. 2020 Jun;38(6):1196-1197.

doi: 10.1097/HJH.0000000000002472.

Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

Jorie Versmissen^{1

2}, Koen Verdonk¹, Melvin Lafeber¹, Johannes P C van den Akker³, Nicole G M Hunfeld^{2

3}, Ewout J Hoorn¹, A H Jan Danser¹

Affiliations

¹ Department of Internal Medicine.
² Department of Hospital Pharmacy.
³ Department of Intensive Care, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

PMID: 32371817
PMCID: PMC7236856
DOI: 10.1097/HJH.0000000000002472

Comment

Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

Jorie Versmissen et al. J Hypertens. 2020 Jun.

. 2020 Jun;38(6):1196-1197.

doi: 10.1097/HJH.0000000000002472.

Authors

Jorie Versmissen^{1

2}, Koen Verdonk¹, Melvin Lafeber¹, Johannes P C van den Akker³, Nicole G M Hunfeld^{2

3}, Ewout J Hoorn¹, A H Jan Danser¹

Affiliations

¹ Department of Internal Medicine.
² Department of Hospital Pharmacy.
³ Department of Intensive Care, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

PMID: 32371817
PMCID: PMC7236856
DOI: 10.1097/HJH.0000000000002472

No abstract available

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Comment in

Reply: Possible impact of membrane ACE2 expression on COVID-19 infection.
Esler M, Esler D. Esler M, et al. J Hypertens. 2020 Jun;38(6):1192-1194. doi: 10.1097/HJH.0000000000002484. J Hypertens. 2020. PMID: 32371814 Free PMC article. No abstract available.

Comment on

Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic?
Esler M, Esler D. Esler M, et al. J Hypertens. 2020 May;38(5):781-782. doi: 10.1097/HJH.0000000000002450. J Hypertens. 2020. PMID: 32195824 No abstract available.

Cited by

No association between use of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers prior to hospital admission and clinical course of COVID-19 in the COvid MEdicaTion (COMET) study.
Sablerolles RSG, Hogenhuis FEF, Lafeber M, van de Loo BPA, Borgsteede SD, Boersma E, Versmissen J, van der Kuy H; COMET Research Team. Sablerolles RSG, et al. Br J Clin Pharmacol. 2021 Aug;87(8):3301-3309. doi: 10.1111/bcp.14751. Epub 2021 Feb 18. Br J Clin Pharmacol. 2021. PMID: 33507556 Free PMC article.
Does intestinal dysbiosis contribute to an aberrant inflammatory response to severe acute respiratory syndrome coronavirus 2 in frail patients?
Terruzzi I, Senesi P. Terruzzi I, et al. Nutrition. 2020 Nov-Dec;79-80:110996. doi: 10.1016/j.nut.2020.110996. Epub 2020 Sep 1. Nutrition. 2020. PMID: 33002653 Free PMC article. Review.
COvid MEdicaTion (COMET) study: protocol for a cohort study.
Sablerolles RSG, Hogenhuis FEF, Lafeber M, van de Loo BPA, Borgsteede SD, Boersma E, Versmissen J, van der Kuy HM; COMET Research team. Sablerolles RSG, et al. Eur J Hosp Pharm. 2020 Jul;27(4):191-193. doi: 10.1136/ejhpharm-2020-002329. Eur J Hosp Pharm. 2020. PMID: 32587077 Free PMC article.
Use of distinct anti-hypertensive drugs and risk for COVID-19 among hypertensive people: A population-based cohort study in Southern Catalonia, Spain.
Vila-Corcoles A, Satue-Gracia E, Ochoa-Gondar O, Torrente-Fraga C, Gomez-Bertomeu F, Vila-Rovira A, Hospital-Guardiola I, de Diego-Cabanes C, Bejarano-Romero F, Rovira-Veciana D, Basora-Gallisa J. Vila-Corcoles A, et al. J Clin Hypertens (Greenwich). 2020 Aug;22(8):1379-1388. doi: 10.1111/jch.13948. Epub 2020 Jul 25. J Clin Hypertens (Greenwich). 2020. PMID: 32710674 Free PMC article.
Influence of prior comorbidities and chronic medications use on the risk of COVID-19 in adults: a population-based cohort study in Tarragona, Spain.
Vila-Córcoles A, Ochoa-Gondar O, Satué-Gracia EM, Torrente-Fraga C, Gomez-Bertomeu F, Vila-Rovira A, Hospital-Guardiola I, de Diego-Cabanes C, Bejarano-Romero F, Basora-Gallisà J. Vila-Córcoles A, et al. BMJ Open. 2020 Dec 10;10(12):e041577. doi: 10.1136/bmjopen-2020-041577. BMJ Open. 2020. PMID: 33303459 Free PMC article.

See all "Cited by" articles

References

1. Zhou FY, Du T, Fan R, Liu G, Liu Y, Xiang Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395:1054–1062. - PMC - PubMed
1. Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science 2020; 367:1444–1448. - PMC - PubMed
1. Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol 2020; doi: 10.1038/s41569-020-0360-5. [Epub ahead of print]. - PMC - PubMed
1. Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; [Epub ahead of print]. - PMC - PubMed
1. Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med 2020; [Epub ahead of print]. - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
Research Materials
- NCI CPTC Antibody Characterization Program
Miscellaneous
- NCI CPTAC Assay Portal

[1] Zhou FY, Du T, Fan R, Liu G, Liu Y, Xiang Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395:1054–1062. - PMC - PubMed

[2] Zhou FY, Du T, Fan R, Liu G, Liu Y, Xiang Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395:1054–1062. - PMC - PubMed

[3] Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science 2020; 367:1444–1448. - PMC - PubMed

[4] Yan R, Zhang Y, Li Y, Xia L, Guo Y, Zhou Q. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science 2020; 367:1444–1448. - PMC - PubMed

[5] Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol 2020; doi: 10.1038/s41569-020-0360-5. [Epub ahead of print]. - PMC - PubMed

[6] Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol 2020; doi: 10.1038/s41569-020-0360-5. [Epub ahead of print]. - PMC - PubMed

[7] Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; [Epub ahead of print]. - PMC - PubMed

[8] Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; [Epub ahead of print]. - PMC - PubMed

[9] Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med 2020; [Epub ahead of print]. - PMC - PubMed

[10] Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med 2020; [Epub ahead of print]. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

Affiliations

Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

Authors

Affiliations

Conflict of interest statement

Comment in

Comment on

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Research Materials

Miscellaneous

Conflict of interest statement

Comment in

Comment on

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Research Materials

Miscellaneous