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Emergence of coronaviruses pathogenic for humans from ancestral bat viruses. Diversification of SARS-CoV,…
Figure 1
Emergence of coronaviruses pathogenic for humans from ancestral bat viruses. Diversification of SARS-CoV, SARS-CoV-2, and MERS-CoV from ancestor viruses by possible genome recombinations is illustrated. Two major variable regions among viral genomes (S and orf8 genes) are indicated. The variations are most probably due to the high recombination potentials of the coronaviruses. For details, refer to the titled review article in this commentary.
Cui J, Li F, Shi ZL.Cui J, et al.Nat Rev Microbiol. 2019 Mar;17(3):181-192. doi: 10.1038/s41579-018-0118-9.Nat Rev Microbiol. 2019.PMID: 30531947Free PMC article.Review.
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