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. 2020 Mar 26:8:Doc03.
doi: 10.3205/id000047. eCollection 2020.

Calculated parenteral initial treatment of bacterial infections: Economic aspects of antibiotic treatment

Michael Wilke  1 , Claudia Hübner  2 , Wolfgang Kämmerer  3
Affiliations

Calculated parenteral initial treatment of bacterial infections: Economic aspects of antibiotic treatment

Michael Wilke et al. GMS Infect Dis. .

Abstract
in English, German

This is the seventeenth chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2nd updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. This chapter analyses economic aspects of antiinfective therapy. Any treatment decision is also a cost decision. In this chapter the authors particularly analyse whether or not there is evidence that certain clinically effective strategies as Antimicrobial Stewardship programs (AMS), guideline adherent initial therapy, early diagnostics, De-escalation, sequence therapy or therapeutic drug monitoring also have benficial economic effects. These can be direct savings or shortening of length of stay to free resources.

Dies ist das siebzehnte Kapitel der von der Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) herausgegebenen S2k Leitlinie „Kalkulierte parenterale Initialtherapie bakterieller Erkrankungen bei Erwachsenen – Update 2018“ in der 2. aktualisierten Fassung.Dieses Kapitel setzt sich mit den ökonomischen Effekten der antiinfektiven Therapie auseinander. Jede Behandlungsentscheidung ist auch eine kostenrelevante Entscheidung. Die Autoren beleuchten insbesondere die Frage, ob es Evidenz dafür gibt, das klinische wirksame Strategien auch ökonomisch günstig sind. Unter anderem werden Antibiotic Stewardship Programme (ABS), Leitlinienadhärenz in der Initialtherapie, De-Eskalation, Sequenztherapie sowie das therapeutische Drug Monitoring. Ökonomisch günstig sind sowohl direkte Kosteneinsparungen als auch die Verkürzung der Verweildauer um Ressourcen schneller wieder bereit zu stellen.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Table 1
Table 1. Overview of economically recommended strategies
See this image and copyright information in PMC

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