Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Apr 20:26:e00450.
doi: 10.1016/j.btre.2020.e00450. eCollection 2020 Jun.

Plant tissue culture as a perpetual source for production of industrially important bioactive compounds

Hema Chandran  1 , Mukesh Meena  1 , Tansukh Barupal  1 , Kanika Sharma  1
Affiliations
Review

Plant tissue culture as a perpetual source for production of industrially important bioactive compounds

Hema Chandran et al. Biotechnol Rep (Amst). .

Abstract

Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.

Keywords: Bioactive compounds; Micropropagation; Nanoparticles; Phytochemicals; Secondary metabolites.

PubMed Disclaimer

References

    1. Winter J.M., Tang Y. Synthetic biological approaches to natural product biosynthesis. Curr. Opin. Biotechnol. 2012;23:736–743. doi: 10.1016/j.copbio.2011.12.016. - DOI - PMC - PubMed
    1. Yuan H., Ma Q., Ye L., Piao G. The traditional medicine and modern medicine from natural products. Molecules. 2016;21(5):559. doi: 10.3390/molecules21050559. - DOI - PMC - PubMed
    1. Nasri H., Baradaran A., Shirzad H., Rafieian-Kopaei M. New concepts in nutraceuticals as alternative for pharmaceuticals. Int. J. Prev. Med. 2014;5(12):1487–1499. - PMC - PubMed
    1. Atanasov A.G., Waltenberger B., Pferschy-Wenzig E.M., Linder T., Wawrosch C., Uhrin P., Temml V., Wang L., Schwaiger S., Heiss E.H., Rollinger J.M. Discovery and resupply of pharmacologically active plant-derived natural products: a review. Biotechnol. Adv. 2015;33(8):1582–1614. doi: 10.1016/j.biotechadv.2015.08.001. - DOI - PMC - PubMed
    1. Schulz V., Hänsel R., Tyler V.E. Springer-Verlag; Berlin: 2001. Rational Phytotherapy. A Physician’s Guide to Herbal Medicine.

LinkOut - more resources