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Comment
. 2020 Aug;52(3):569-570.
doi: 10.1111/apt.15814. Epub 2020 Jun 3.

Letter: intestinal inflammation, COVID-19 and gastrointestinal ACE2-exploring RAS inhibitors

Mayur Garg  1   2   3 , Simon G Royce  4 , John S Lubel  5
Affiliations
Comment

Letter: intestinal inflammation, COVID-19 and gastrointestinal ACE2-exploring RAS inhibitors

Mayur Garg et al. Aliment Pharmacol Ther. 2020 Aug.

Abstract

LINKED CONTENT

This article is linked to Taxonera et al papers. To view these articles, visit https://doi.org/10.1111/apt.15804 and https://doi.org/10.1111/apt.15893.

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Figures

Figure 1
Figure 1
Effect of ACE inhibitors and angiotensin receptor blockers (ARBs) on (A) ACE2 mRNA expression, (B) activity and (C) immunohistochemical staining intensity in patients with and without IBD who underwent colonoscopic biopsies. No significant differences were noted. Blue circles represent ACE inhibitor use, green circles indicate ARB use
See this image and copyright information in PMC

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References

    1. Taxonera C, Sagastagoitia I, Alba C, Mañas N, Olivares D, Rey E. 2019 novel coronavirus disease (COVID‐19) in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2020. Accepted Author Manuscript. 10.1111/apt.15804 - DOI - PMC - PubMed
    1. Effenberger M, Grabherr F, Mayr L, et al. Faecal calprotectin indicates intestinal inflammation in COVID‐19. Gut. 2020. 10.1136/gutjnl-2020-321388 - DOI - PMC - PubMed
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    1. Garg M, Royce SG, Tikellis C, et al. Imbalance of the renin‐angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target? Gut. 2020;69:841‐851 - PubMed
    1. Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H. Evidence for gastrointestinal infection of SARS‐CoV‐2. Gastroenterology. 2020. - PMC - PubMed

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