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. 2020 May;19(3):355-358.
doi: 10.1016/j.jcf.2020.04.012. Epub 2020 Apr 25.

A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis

Rebecca Cosgriff  1 , Susannah Ahern  2 , Scott C Bell  3 , Keith Brownlee  4 , Pierre-Régis Burgel  5 , Cass Byrnes  6 , Harriet Corvol  7 , Stephanie Y Cheng  8 , Alexander Elbert  9 , Albert Faro  9 , Christopher H Goss  10 , Vincent Gulmans  11 , Bruce C Marshall  9 , Edward McKone  12 , Peter G Middleton  13 , Rasa Ruseckaite  2 , Anne L Stephenson  14 , Siobhán B Carr  15 ; Global Registry Harmonization Group
Collaborators, Affiliations

A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis

Rebecca Cosgriff et al. J Cyst Fibros. 2020 May.

Abstract

Information is lacking on the clinical impact of the novel coronavirus, SARS-CoV-2, on people with cystic fibrosis (CF). Our aim was to characterise SARS-CoV-2 infection in people with cystic fibrosis.

Methods: Anonymised data submitted by each participating country to their National CF Registry was reported using a standardised template, then collated and summarised.

Results: 40 cases have been reported across 8 countries. Of the 40 cases, 31 (78%) were symptomatic for SARS-CoV-2 at presentation, with 24 (60%) having a fever. 70% have recovered, 30% remain unresolved at time of reporting, and no deaths have been submitted.

Conclusions: This early report shows good recovery from SARS-CoV-2 in this heterogeneous CF cohort. The disease course does not seem to differ from the general population, but the current numbers are too small to draw firm conclusions and people with CF should continue to strictly follow public health advice to protect themselves from infection.

Keywords: Coronavirus; Cystic fibrosis; SARS-CoV-2.

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Conflict of interest statement

Declaration of Competing Interest The authors have no conflicts of interest to declare relating to this work.

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