Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct;22(5):e13308.
doi: 10.1111/tid.13308. Epub 2020 Jul 7.

Perinephric abscess in a renal transplant recipient due to Mycoplasma hominis: Case report and review of the literature

Matthew Adams  1 , Rory Bouzigard  2 , Mohanad Al-Obaidi  1 , Tirdad T Zangeneh  1
Affiliations
Review

Perinephric abscess in a renal transplant recipient due to Mycoplasma hominis: Case report and review of the literature

Matthew Adams et al. Transpl Infect Dis. 2020 Oct.

Abstract

A 42-year-old man presented with nausea, malaise, and pain at his renal graft site 4 months following deceased donor renal transplant. His transplantation had been complicated by urinary leak with delayed wound closure requiring ureteral revision with biologic mesh placement. The initial evaluation in the hospital revealed urinalysis with significant pyuria as well as abdominal CT imaging concerning for abscess formation anterior to the grafted kidney. Interventional radiology (IR) guided drainage of this abscess yielded growth of Enterococcus faecalis treated with intravenous ampicillin/sulbactam. He continued to have pain at his graft site and repeat imaging revealed a persistent abscess despite prolonged antimicrobial therapy. Urine cultures isolated Mycoplasma species. A repeat aspirate of abscess fluid collected and Mycoplasma hominis was identified by molecular test. Patient's symptoms abated and his abscess completely resolved on repeat imaging after completing a course of oral moxifloxacin and doxycycline. His immunosuppression did not require adjustment and the renal graft continued to function well following this therapy. Mycoplasma and Ureaplasma should be considered as a potential etiology for perinephric abscess in renal transplant recipients.

Keywords: Mycoplasma hominis; Ureaplasma; perinephric abscess; renal transplant.

PubMed Disclaimer

References

REFERENCES

    1. Martin DH. Genital Mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma species. In: Bennett JE, Dolin R, Blaser MJ eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (8th ed.). Philadelphia, PA: Elsevier Suanders.2030-2034.
    1. Smibert OC, Wilson HL, Sohail A, et al. Donor-derived Mycoplasma hominis and an apparent cluster of M hominis cases in solid organ transplant recipients. Clin Infect Dis. 2017;65(9):1504-1508.
    1. Meyer RD, Clough W. Extragenital Mycoplasma hominis infections in adults: emphasis on immunosuppression. Clin Infect Dis. 1993;17(suppl 1):S243-S249.
    1. Taylor-Robinson D, McCormack WM. The genital Mycoplasmas. N Engl J Med. 1980;302:1003-1010.
    1. Eilers E, Moter A, Bollmann R, et al. Ureaplasma and Mycoplasma in kidney allograft recipients-A case series and review of the literature. Transpl Infect Dis. 2018;20(5):e12937.

LinkOut - more resources