Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis

Charlotte Steenblock¹, Vladimir Todorov², Waldemar Kanczkowski², Graeme Eisenhofer^{2

3}, Andreas Schedl⁴, Ma-Li Wong⁵, Julio Licinio⁵, Michael Bauer⁶, Allan H Young⁷, Raul R Gainetdinov^{8

9}, Stefan R Bornstein^{2

10}

Affiliations

¹ Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. charlotte.steenblock@uniklinikum-dresden.de.
² Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
³ Institute of Clinical Chemistry, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
⁴ Université Côte d'Azur, INSERM, CNRS, iBV, Nice, France.
⁵ State University of New York, Upstate Medical University, Syracuse, NY, USA.
⁶ Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.
⁷ Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
⁸ Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia.
⁹ St. Petersburg State University Hospital, St. Petersburg State University, St. Petersburg, Russia.
¹⁰ Diabetes and Nutritional Sciences Division, King's College London, London, UK.

Editorial

Charlotte Steenblock et al. Mol Psychiatry. 2020 Aug.

. 2020 Aug;25(8):1611-1617.

doi: 10.1038/s41380-020-0758-9. Epub 2020 May 7.

¹ Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. charlotte.steenblock@uniklinikum-dresden.de.
² Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
³ Institute of Clinical Chemistry, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
⁴ Université Côte d'Azur, INSERM, CNRS, iBV, Nice, France.
⁵ State University of New York, Upstate Medical University, Syracuse, NY, USA.
⁶ Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.
⁷ Centre for Affective Disorders, Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
⁸ Institute of Translational Biomedicine, St. Petersburg State University, St. Petersburg, Russia.
⁹ St. Petersburg State University Hospital, St. Petersburg State University, St. Petersburg, Russia.
¹⁰ Diabetes and Nutritional Sciences Division, King's College London, London, UK.

No abstract available

Conflict of interest statement

The authors declare that they have no conflict of interest.

1. Cameron HA, Schoenfeld TJ. Behavioral and structural adaptations to stress. Front Neuroendocrinol. 2018;49:106–13. doi: 10.1016/j.yfrne.2018.02.002. - DOI - PMC - PubMed
1. Licinio J, Wong ML. The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection. Mol Psychiatry. 1999;4:317–27. doi: 10.1038/sj.mp.4000586. - DOI - PubMed
1. Nemeroff CB, Goldschmidt-Clermont PJ. Heartache and heartbreak-the link between depression and cardiovascular disease. Nat Rev Cardiol. 2012;9:526–39. doi: 10.1038/nrcardio.2012.91. - DOI - PubMed
1. Reiche EM, Nunes SO, Morimoto HK. Stress, depression, the immune system, and cancer. Lancet Oncol. 2004;5:617–25. doi: 10.1016/S1470-2045(04)01597-9. - DOI - PubMed
1. Sternberg EM, Chrousos GP, Wilder RL, Gold PW. The stress response and the regulation of inflammatory disease. Ann Intern Med. 1992;117:854–66. doi: 10.7326/0003-4819-117-10-854. - DOI - PubMed