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. 2020 Jun;99(6):1419-1420.
doi: 10.1007/s00277-020-04066-7. Epub 2020 May 8.

Signals of Th2 immune response from COVID-19 patients requiring intensive care

Luca Roncati  1 , Vincenzo Nasillo  2 , Beatrice Lusenti  2 , Giovanni Riva  2
Affiliations

Signals of Th2 immune response from COVID-19 patients requiring intensive care

Luca Roncati et al. Ann Hematol. 2020 Jun.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Cytological signals of Th2 immune response on peripheral blood smears from COVID-19 patients requiring intensive care: a on the right side of the panel, three eosinophils in a row accompanied by a basophile in the upper left corner (× 40 objective); b an eosinophil in the degranulation phase (× 100 objective); c a bilobed degranulated eosinophil in the center of the panel (× 100 objective); d an immature plasma cell (Türk cell) in the midst of prominent rouleaux (× 100 objective) (May-Grünwald stain)
See this image and copyright information in PMC

References

    1. Spellberg B, Edwards JE., Jr Type 1 / type 2 immunity in infectious diseases. Clin Infect Dis. 2001;32(1):76–102. doi: 10.1086/317537. - DOI - PubMed
    1. Rosenberg HF, Dyer KD, Domachowske JB. Eosinophils and their interactions with respiratory virus pathogens. Immunol Res. 2009;43(1–3):128–137. doi: 10.1007/s12026-008-8058-5. - DOI - PMC - PubMed
    1. Zhang C, Wu Z, Li JW, Zhao H, Wang GQ (2020) The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality. Int J Antimicrob Agents:105954. 10.1016/j.ijantimicag.2020.105954 - PMC - PubMed
    1. Song Y, Shen H, Schenten D, Shan P, Lee PJ, Goldstein DR. Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2012;32(1):103–109. doi: 10.1161/ATVBAHA.111.236349. - DOI - PMC - PubMed
    1. Wei XS, Wang X, Niu YR, Ye LL, Peng WB, Wang ZH, Yang WB, Yang BH, Zhang JC, Ma WL, Wang XR, Zhou Q (2020) Clinical characteristics of SARS-CoV-2 infected pneumonia with diarrhea. Lancet Respir Med SSRN. 10.2139/ssrn.3546120

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