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Review
. 2020 Aug;353(8):e2000025.
doi: 10.1002/ardp.202000025. Epub 2020 May 8.

Coumarin derivatives with anticancer activities: An update

Xu-Feng Song  1 , Jing Fan  2 , Lan Liu  3 , Xiao-Feng Liu  4 , Feng Gao  5
Affiliations
Review

Coumarin derivatives with anticancer activities: An update

Xu-Feng Song et al. Arch Pharm (Weinheim). 2020 Aug.

Abstract

Cancer can invade or spread to almost all parts of the body. The increasing morbidity and high mortality of cancer create a great demand for the development of novel anticancer drugs. Coumarin derivatives are ubiquitous in nature and can readily interact with diverse enzymes and receptors in cancer cells via weak bond interactions; hence, coumarin is a highly privileged pharmacophore for the development of novel anticancer agents. This review will focus on the recent development of coumarin hybrids as potential anticancer agents covering articles published from 2019 to 2020.

Keywords: anticancer; coumarin; drug discovery; mechanism of action.

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References

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