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Meta-Analysis
. 2020 Aug;26(8):1839-1841.
doi: 10.3201/eid2608.201160. Epub 2020 May 8.

Prognostic Value of Leukocytosis and Lymphopenia for Coronavirus Disease Severity

Glen Huang, Alex J Kovalic, Christopher J Graber
Meta-Analysis

Prognostic Value of Leukocytosis and Lymphopenia for Coronavirus Disease Severity

Glen Huang et al. Emerg Infect Dis. 2020 Aug.

Abstract

To evaluate lymphopenia as a marker for coronavirus disease severity, we conducted a meta-analysis of 10 studies. Severe illness was associated with lower lymphocyte and higher leukocyte counts. Using these markers for early identification of patients with severe disease may help healthcare providers prioritize the need to obtain therapy.

Keywords: 2019 novel coronavirus disease; COVID-19; SARS-CoV-2; coronavirus disease; leukocytosis; lymphopenia; meta-analysis; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

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