Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 May 8;20(1):109.
doi: 10.1186/s12871-020-01026-6.

A case of an unexpected posterior mediastinal functional paraganglioma: case report and literature review

Affiliations
Review

A case of an unexpected posterior mediastinal functional paraganglioma: case report and literature review

Zhuqing Yang et al. BMC Anesthesiol. .

Abstract

Background: Paraganglioma can be found in a wide range of locations. However, paraganglioma in the posterior mediastinum is rare. An unexpected paraganglioma located in the posterior mediastinum was found during surgery. The anesthesia management of this patient was challenging.

Case presentation: A 65-year-old male with a posterior mediastinal tumor was scheduled for thoracoscopic mediastinal tumor resection. Severe hemodynamic changes during the operation and postoperative pathological diagnosis showed that the patient had a rare case of posterior mediastinal functional paraganglioma, which was not found before the operation. Although the patient did not experience side effects after surgery, he did experience a dangerous surgical process.

Conclusions: The correct diagnosis of paraganglioma, intensive preoperative screening, adequate preoperative preparation, and accurate intraoperative anesthesia management could provide better anesthesia for paraganglioma patients.

Keywords: Mediastinal tumor; Paraganglioma; Pheochromocytoma.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Chest CT. The size of tumor was approximately 4.1 cm × 3.2 cm in the left spinal column, and the enhanced scan showed uniform enhancement
Fig. 2
Fig. 2
Pathology diagnosed the posterior mediastinum tumor as PGL. a Postoperative pathology showed a patchy distribution of tumor cells with blue-purple cytoplasm and abundant interstitial blood sinuses. b CD56(+); c CgA(+); d SYN(+)

References

    1. Gunawardane PTK, Grossman A. Phaeochromocytoma and paraganglioma. Adv Exp Med Biol. 2017;956:239–259. doi: 10.1007/5584_2016_76. - DOI - PubMed
    1. Neumann HPH, Longo DL, Young WF, Eng C. Pheochromocytoma and Paraganglioma. N Engl J Med. 2019;381:552–565. doi: 10.1056/NEJMra1806651. - DOI - PubMed
    1. Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, et al. Pheochromocytoma and paraganglioma: an endcrine society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(6):1915–1942. doi: 10.1210/jc.2014-1498. - DOI - PubMed
    1. Bülow B, Ahrén B. Swedish Research Council Study Group of Endocrine Abdominal Tumours Adrenal incidentaloma experience of a standardized diagnostic programme in the Swedish prospective study. J Intern Med. 2002;252:239–246. doi: 10.1046/j.1365-2796.2002.01028.x. - DOI - PubMed
    1. Kasperlik-Zaluska AA, Roslonowska E, Slowinska-Srzednicka J, OTTO M, Cichocki A, Cwikla J, et al. 1,111 patients with adrenal incidentalomas observed at a single endocrinological center: incidence of chromaffin tumors. Ann N Y Acad Sci. 2006;1073:38–46. doi: 10.1196/annals.1353.004. - DOI - PubMed

LinkOut - more resources