Inflammation's Epigenetic Footprint in Hematopoietic Stem Cells
- PMID: 32386549
- DOI: 10.1016/j.stem.2020.04.015
Inflammation's Epigenetic Footprint in Hematopoietic Stem Cells
Abstract
Immune memory was thought to be unique to cells of the adaptive immune system. In this issue of Cell Stem Cell, de Laval et al. (2020) describe persistent epigenetic modifications in hematopoietic stem cells following an inflammatory insult with LPS as a mechanism by which immune memory may be established.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
-
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells.Cell Stem Cell. 2020 May 7;26(5):657-674.e8. doi: 10.1016/j.stem.2020.01.017. Epub 2020 Mar 12. Cell Stem Cell. 2020. PMID: 32169166
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
