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Comment
. 2020 Jun;41(6):454-456.
doi: 10.1016/j.it.2020.04.010. Epub 2020 May 6.

Resident Memory T Cells Escape 'Home Quarantine'

Marco Künzli  1 , Carolyn G King  2
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Resident Memory T Cells Escape 'Home Quarantine'

Marco Künzli et al. Trends Immunol. 2020 Jun.

Abstract

T resident memory (Trm) cells provide a first line of defense in non-lymphoid tissues. A new report in Nature Immunology by Fonseca et al. reveals that CD8+ Trm cells can give rise to circulating effector and memory T cells, but remain predisposed to migrate back into their tissue of origin.

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