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Editorial
. 2020 May;36(5):591-592.
doi: 10.1016/j.cjca.2020.03.025. Epub 2020 Mar 29.

A New Look At the Mosaic Theory of Hypertension

Rhian M Touyz  1 , Ross D Feldman  2 , David G Harrison  3 , Ernesto L Schiffrin  4
Affiliations
Editorial

A New Look At the Mosaic Theory of Hypertension

Rhian M Touyz et al. Can J Cardiol. 2020 May.
No abstract available

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Conflict of interest statement

Disclosures

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Different aspects of Irving Page’s mosaic theory of hypertension revisited in this compendium. The 4 black elements are the principal components mentioned in the original 1949 paper. The 8 blue components are enumerated in the subsequent, more extensive revisiting of the theme in 1982. The 8 red components are themes dealt with by review papers in the current issue of the Canadian Journal of Cardiology.
See this image and copyright information in PMC

References

    1. Page IH. Pathogenesis of arterial hypertension. J Am Med Assoc 1949;140:451–8. - PubMed
    1. Page IH. The mosaic theory 32 years later. Hypertension 1982;4:177. - PubMed
    1. Harrison DG. The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension. J Am Soc Hypertens 2013;7:68–74. - PMC - PubMed
    1. Lip S, Padmanabhan S. Genomics of blood pressure and hypertension: extending the mosaic theory towards stratification. Can J Cardiol 2020;36:694–705. - PMC - PubMed
    1. Feldman RD. Sex-specific determinants of coronary artery disease and atherosclerotic risk factors: estrogen and beyond. Can J Cardiol 2020;36: 706–11. - PubMed

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