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Comment
. 2020 Jul;16(7):350.
doi: 10.1038/s41582-020-0367-x.

APOE*ε4 is linked to BBB breakdown

Affiliations
Comment

APOE*ε4 is linked to BBB breakdown

Heather Wood. Nat Rev Neurol. 2020 Jul.
No abstract available

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Comment on

  • APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
    Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV. Montagne A, et al. Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29. Nature. 2020. PMID: 32376954 Free PMC article.

References

Original article
    1. Montagne, A. et al. APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline. Nature 581, 71–76 (2020) - DOI
Related articles
    1. Sweeney, M. D. et al. Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders. Nat. Rev. Neurol. 14, 133–150 (2018) - DOI
    1. Yamazaki, Y. et al. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies. Nat. Rev. Neurol. 15, 501–518 (2019) - DOI

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