Keynote 42: Pembrolizumab, PD-L1, and where to draw the line
- PMID: 32395561
- PMCID: PMC7210198
- DOI: 10.21037/atm.2020.01.65
Keynote 42: Pembrolizumab, PD-L1, and where to draw the line
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.01.65). NR: Advisory role with Merck, BMS, AZ, Genentech, AbbVie, Celgene; JC: Speaking role with Merck, Advisory role with AstraZeneca, Guardant, Merck, Eli Lilly, Pfizer, and NGM Biopharmaceuticals. Travel compensation from Merck, AstraZeneca, Pfizer, and NGM bio. Board of Directors-Lung Cancer Initiative of North Carolina (uncompensated). Trial PI for: Bristol-Myers Squibb, Eli Lilly, Genentech, Spectrum, Adaptimmune, Medpacto, Bayer, AbbVie, Moderna, GlaxoSmithKline, Array, and AstraZeneca. JI has no conflicts of interest to declare.
Comment on
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Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial.Lancet. 2019 May 4;393(10183):1819-1830. doi: 10.1016/S0140-6736(18)32409-7. Epub 2019 Apr 4. Lancet. 2019. PMID: 30955977 Clinical Trial.
References
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- Mok TSK, Wu YL, Kudaba I, et al. Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial. Lancet 2019;393:1819-30. 10.1016/S0140-6736(18)32409-7 - DOI - PubMed
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