Microbial Diagnostics for Cancer: A Step Forward but Not Prime Time Yet

Cynthia L Sears¹, Steven L Salzberg²

Affiliations

¹ Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Bloomberg-Kimmel Institute of Cancer Immunotherapy, Department of Molecular Microbiology & Immunology, Bloomberg School of Public Health, Baltimore, MD 21231, USA. Electronic address: csears@jhmi.edu.
² Departments of Biomedical Engineering, Computer Science, and Biostatistics, Johns Hopkins University, Baltimore, MD 21211, USA. Electronic address: salzberg@jhu.edu.

PMID: 32396856
DOI: 10.1016/j.ccell.2020.04.010

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Microbial Diagnostics for Cancer: A Step Forward but Not Prime Time Yet

Cynthia L Sears et al. Cancer Cell. 2020.

Free article

. 2020 May 11;37(5):625-627.

doi: 10.1016/j.ccell.2020.04.010.

Authors

Cynthia L Sears¹, Steven L Salzberg²

Affiliations

¹ Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Bloomberg-Kimmel Institute of Cancer Immunotherapy, Department of Molecular Microbiology & Immunology, Bloomberg School of Public Health, Baltimore, MD 21231, USA. Electronic address: csears@jhmi.edu.
² Departments of Biomedical Engineering, Computer Science, and Biostatistics, Johns Hopkins University, Baltimore, MD 21211, USA. Electronic address: salzberg@jhu.edu.

PMID: 32396856
DOI: 10.1016/j.ccell.2020.04.010

Abstract

Translational microbiome science in humans has not yet fully realized its clinical potentials. The analyses by Poore et al. in Nature offer a strong foundation on which to begin to build microbial diagnostics to detect cancer.

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Microbiome analyses of blood and tissues suggest cancer diagnostic approach.
Poore GD, Kopylova E, Zhu Q, Carpenter C, Fraraccio S, Wandro S, Kosciolek T, Janssen S, Metcalf J, Song SJ, Kanbar J, Miller-Montgomery S, Heaton R, Mckay R, Patel SP, Swafford AD, Knight R. Poore GD, et al. Nature. 2020 Mar;579(7800):567-574. doi: 10.1038/s41586-020-2095-1. Epub 2020 Mar 11. Nature. 2020. Retraction in: Nature. 2024 Jul;631(8021):694. doi: 10.1038/s41586-024-07656-x. PMID: 32214244 Free PMC article. Retracted.

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Microbial Diagnostics for Cancer: A Step Forward but Not Prime Time Yet

Affiliations

Microbial Diagnostics for Cancer: A Step Forward but Not Prime Time Yet

Authors

Affiliations

Abstract

Comment on

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Medical