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. 2020 Jul 2;56(1):2001190.
doi: 10.1183/13993003.01190-2020. Print 2020 Jul.

Risk factors for viral RNA shedding in COVID-19 patients

Yu Fu  1   2 , Ping Han  3   2 , Rui Zhu  4   2 , Tao Bai  5   2 , Jianhua Yi  6 , Xi Zhao  1 , Meihui Tao  7 , Runze Quan  1 , Chaoyue Chen  1 , Ying Zhang  1 , Qin He  3 , Mengjia Jing  3 , Xiaofeng Xiong  3 , Dean Tian  3 , Wei Yan  8
Affiliations

Risk factors for viral RNA shedding in COVID-19 patients

Yu Fu et al. Eur Respir J. .

Abstract

The median time of SARS-CoV-2 viral RNA shedding was 19 days. Patients with coronary heart disease comorbidity or decreased albumin levels experienced delays in clearance of SARS-CoV-2 RNA. https://bit.ly/2zjQu64

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Conflict of interest statement

Conflict of interest: Y. Fu has nothing to disclose. Conflict of interest: P. Han has nothing to disclose. Conflict of interest: R. Zhu has nothing to disclose. Conflict of interest: T. Bai has nothing to disclose. Conflict of interest: J. Yi has nothing to disclose. Conflict of interest: X. Zhao has nothing to disclose. Conflict of interest: M. Tao has nothing to disclose. Conflict of interest: R. Quan has nothing to disclose. Conflict of interest: C. Chen has nothing to disclose. Conflict of interest: Y. Zhang has nothing to disclose. Conflict of interest: Q. He has nothing to disclose. Conflict of interest: M. Jing has nothing to disclose. Conflict of interest: X. Xiong has nothing to disclose. Conflict of interest: D. Tian has nothing to disclose. Conflict of interest: W. Yan has nothing to disclose.

Figures

FIGURE 1
FIGURE 1
Kaplan–Meier curves showing the proportions of SARS-CoV-2 RNA-positive patients. T1 refers to the duration from the symptom onset to the day when SARS-CoV-2 RNA was negative for two consecutive times, which was considered to indicate an undetectable viral RNA level. a) All patients (n=410). b) Patients with (n=27) and without (n=383) coronary heart disease; p=0.029. c) Patients with albumin levels <35 g·L−1 (n=193) and ≥35 g·L−1 (n=217); p=0.032. d) Patients who started antiviral therapy >7 days (n=128) and ≤7 days (n=278) after symptom onset; p<0.001.
See this image and copyright information in PMC

References

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