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. 2020 May 12;10(1):7841.
doi: 10.1038/s41598-020-64884-7.

Association between serum uric acid and metabolic syndrome: a cross-sectional study in Bangladeshi adults

Nurshad Ali  1 , Rakib Miah  2 , Mahmudul Hasan  2 , Zitu Barman  2 , Ananya Dutta Mou  2 , Jaasia Momtahena Hafsa  2 , Aporajita Das Trisha  2 , Akibul Hasan  2 , Farjana Islam  2
Affiliations

Association between serum uric acid and metabolic syndrome: a cross-sectional study in Bangladeshi adults

Nurshad Ali et al. Sci Rep. .

Abstract

Elevated levels of serum uric acid (SUA) have been suggested to associate with cardiovascular disease, diabetes and metabolic syndrome (MetS). However, information is limited on the association between SUA and MetS in general adults. This study aimed to assess the relationship of SUA with MetS and its components in general adults in Bangladesh. A total of 420 participants were enrolled in this study and biochemical parameters including SUA, fasting blood glucose (FBG) and lipid profile were analyzed using standard methods. The NECP criteria were applied to define MetS. The association of SUA with MetS and its components were evaluated by multinomial logistic regression models. The overall prevalence of MetS was 22% with 21.9% in males and 22.1% in female participants. Male subjects had a high prevalence of elevated components of MetS than in the female subjects (p < 0.05 for all cases). The mean concentration of SUA was significantly higher in subjects of the MetS group compared to the non-MetS group (p < 0.05). The components of MetS were raised with the increasing concentrations of SUA across the quartiles. In regression analysis, SUA was significantly associated with the prevalence of MetS in Bangladeshi adults. In conclusion, elevated SUA was significantly associated with the prevalence of MetS and its components.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Prevalence of MetS and its components in the hyperuricemic and non-hyperuricemic group. P < 0.05 for all cases when the prevalence of MetS and its component are compared between the groups. P-values are obtained from the Chi-square test.
See this image and copyright information in PMC

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