Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology

doi:10.1164/rccm.202004-1385ED

Editorial

. 2020 Jul 1;202(1):1-4.

doi: 10.1164/rccm.202004-1385ED.

Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology

Hannah Wunsch^{1

2

3}

Affiliations

¹ Department of Critical Care Medicine Sunnybrook Health Sciences Centre Toronto, Ontario, Canada Sunnybrook Research InstituteToronto, Ontario, Canada.
² Department of Anesthesia and Pain Medicineand.
³ Interdepartmental Division of Critical Care MedicineUniversity of Toronto Toronto, Ontario, Canada.

PMID: 32402207
PMCID: PMC7328308
DOI: 10.1164/rccm.202004-1385ED

Editorial

Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology

Hannah Wunsch. Am J Respir Crit Care Med. 2020.

. 2020 Jul 1;202(1):1-4.

doi: 10.1164/rccm.202004-1385ED.

Author

Hannah Wunsch^{1

2

3}

Affiliations

¹ Department of Critical Care Medicine Sunnybrook Health Sciences Centre Toronto, Ontario, Canada Sunnybrook Research InstituteToronto, Ontario, Canada.
² Department of Anesthesia and Pain Medicineand.
³ Interdepartmental Division of Critical Care MedicineUniversity of Toronto Toronto, Ontario, Canada.

PMID: 32402207
PMCID: PMC7328308
DOI: 10.1164/rccm.202004-1385ED

No abstract available

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Figures

**Figure 1.**
Mortality with use of invasive mechanical ventilation (IMV) for patients with coronavirus disease (COVID-19). The red line represents the expected increasing mortality associated with COVID-19 as age or number and severity of comorbidities increases; the black line represents the idealized ability to reduce mortality to the same low rate for all, irrespective of patient characteristics. The blue line represents the likely differential impact of IMV with more benefit for those who are younger and healthier at baseline and less benefit for those who are older and with more underlying health issues.

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References

1. Warwicker P. Polio: the story of the great polio epidemic in Copenhagen in 1952. Copenhagen, Denmark: Gyldendal; 2006.
1. Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med [online ahead of print] 14 Apr 2020; DOI: 10.1007/s00134-020-06033-2. - PMC - PubMed
1. Wang Y, Lu X, Chen H, Chen T, Su N, Huang F, et al. Clinical course and outcomes of 344 intensive care patients with COVID-19. Am J Respir Crit Care Med. [online ahead of print] 8 Apr 2020; DOI: 10.1164/rccm.202003-0736LE. - PMC - PubMed
1. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area. JAMA. 2020;323:2052–2059. - PMC - PubMed
1. Bellani G, Laffey JG, Pham T, Madotto F, Fan E, Brochard L, et al. LUNG SAFE Investigators; ESICM Trials Group. Noninvasive ventilation of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study. Am J Respir Crit Care Med. 2017;195:67–77. - PubMed

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[1] Warwicker P. Polio: the story of the great polio epidemic in Copenhagen in 1952. Copenhagen, Denmark: Gyldendal; 2006.

[2] Warwicker P. Polio: the story of the great polio epidemic in Copenhagen in 1952. Copenhagen, Denmark: Gyldendal; 2006.

[3] Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med [online ahead of print] 14 Apr 2020; DOI: 10.1007/s00134-020-06033-2. - PMC - PubMed

[4] Gattinoni L, Chiumello D, Caironi P, Busana M, Romitti F, Brazzi L, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med [online ahead of print] 14 Apr 2020; DOI: 10.1007/s00134-020-06033-2. - PMC - PubMed

[5] Wang Y, Lu X, Chen H, Chen T, Su N, Huang F, et al. Clinical course and outcomes of 344 intensive care patients with COVID-19. Am J Respir Crit Care Med. [online ahead of print] 8 Apr 2020; DOI: 10.1164/rccm.202003-0736LE. - PMC - PubMed

[6] Wang Y, Lu X, Chen H, Chen T, Su N, Huang F, et al. Clinical course and outcomes of 344 intensive care patients with COVID-19. Am J Respir Crit Care Med. [online ahead of print] 8 Apr 2020; DOI: 10.1164/rccm.202003-0736LE. - PMC - PubMed

[7] Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area. JAMA. 2020;323:2052–2059. - PMC - PubMed

[8] Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area. JAMA. 2020;323:2052–2059. - PMC - PubMed

[9] Bellani G, Laffey JG, Pham T, Madotto F, Fan E, Brochard L, et al. LUNG SAFE Investigators; ESICM Trials Group. Noninvasive ventilation of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study. Am J Respir Crit Care Med. 2017;195:67–77. - PubMed

[10] Bellani G, Laffey JG, Pham T, Madotto F, Fan E, Brochard L, et al. LUNG SAFE Investigators; ESICM Trials Group. Noninvasive ventilation of patients with acute respiratory distress syndrome: insights from the LUNG SAFE study. Am J Respir Crit Care Med. 2017;195:67–77. - PubMed

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Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology

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Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology

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