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Case Reports
. 2020 Jul;29(7):104865.
doi: 10.1016/j.jstrokecerebrovasdis.2020.104865. Epub 2020 May 11.

Acute Thrombocytopenia After Tissue Plasminogen Activator for Stroke

Jonathan Morena  1 , Casey May  2 , Tamara Strohm  3
Affiliations
Case Reports

Acute Thrombocytopenia After Tissue Plasminogen Activator for Stroke

Jonathan Morena et al. J Stroke Cerebrovasc Dis. 2020 Jul.

Abstract

We present what may be the first case report of acute thrombocytopenia after tissue plasminogen activator (tPA) in the setting of stroke. Early fibrinogen degradation coagulopathy (EFDC) after tPA has been described in the past and acute thrombocytopenia may fall into this spectrum. Further studies are needed to evaluate the bleeding and mortality risk associated with thrombocytopenia after tPA.

Keywords: Coagulopathy; Complications; Thrombocytopenia; Tissue plasminogen activator.

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