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. 2020 Jul;91(7):779-780.
doi: 10.1136/jnnp-2020-322992. Epub 2020 May 13.

Progression of cognitive and behavioural impairment in early amyotrophic lateral sclerosis

Emma Beeldman #  1 , Rosanne Govaarts #  2 , Marianne de Visser  2 , Michelle Klein Twennaar  2 , Anneke J van der Kooi  2 , Leonard H van den Berg  3 , Jan H Veldink  3 , Yolande A L Pijnenburg  2 , Rob J de Haan  4 , Ben A Schmand  5 , Joost Raaphorst  2
Affiliations

Progression of cognitive and behavioural impairment in early amyotrophic lateral sclerosis

Emma Beeldman et al. J Neurol Neurosurg Psychiatry. 2020 Jul.
No abstract available

Keywords: ALS; behavioural disorder; cognition; frontotemporal dementia.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Category shifts among patients with ALS at follow-up. Proportions of patients with ALS (n=28) with no (green), mild (blue) or severe (red and pink) cognitive and/or behavioural impairment at baseline (upper bar) and follow-up (lower bar). Severe behavioural impairment is compatible with the behavioural variant of frontotemporal dementia. Ten patients shifted towards a more severe category: six from ‘no’ to ‘mild’ cognitive impairment, one from ‘no’ to ‘mild’ behavioural impairment, two from ‘no’ to ‘severe’ behavioural impairment and one from ‘no’ to ‘mild’ cognitive impairment and ‘severe’ behavioural impairment. ALS, amyotrophic lateral sclerosis.
See this image and copyright information in PMC

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